ID A0A0C3RH27_9PORP Unreviewed; 443 AA.
AC A0A0C3RH27;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Multidrug-efflux transporter {ECO:0000256|ARBA:ARBA00031636};
GN ORFNames=BA92_07840 {ECO:0000313|EMBL:KIO44919.1}, DMB45_12180
GN {ECO:0000313|EMBL:PXZ43140.1};
OS Sanguibacteroides justesenii.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Porphyromonadaceae;
OC Sanguibacteroides.
OX NCBI_TaxID=1547597 {ECO:0000313|EMBL:KIO44919.1, ECO:0000313|Proteomes:UP000031980};
RN [1] {ECO:0000313|EMBL:KIO44919.1, ECO:0000313|Proteomes:UP000031980}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUH 308042 {ECO:0000313|EMBL:KIO44919.1,
RC ECO:0000313|Proteomes:UP000031980};
RA Sydenham T.V., Hasman H., Justensen U.S.;
RT "Porphyromonadaceae bacterium OUH 308042 = ATCC BAA-2681 = DSM 28342 draft
RT genome.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:PXZ43140.1, ECO:0000313|Proteomes:UP000248308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OUH 969102 {ECO:0000313|EMBL:PXZ43140.1,
RC ECO:0000313|Proteomes:UP000248308};
RX PubMed=25814588;
RA Sydenham T.V., Hasman H., Justesen U.S.;
RT "Draft Genome Sequences of Sanguibacteroides justesenii, gen. nov., sp.
RT nov., Strains OUH 308042T (= ATCC BAA-2681T) and OUH 334697 (= ATCC BAA-
RT 2682), Isolated from Blood Cultures from Two Different Patients.";
RL Genome Announc. 3:e00005-15(2015).
RN [3] {ECO:0000313|EMBL:PXZ43140.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=OUH 969102 {ECO:0000313|EMBL:PXZ43140.1};
RA Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M.,
RA Wayne K.J., Tettelin H., Glass J.I., Rusch D., Podicherti R., Tsui H.-C.T.,
RA Winkler M.E.;
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIO44919.1}.
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DR EMBL; JPIU01000038; KIO44919.1; -; Genomic_DNA.
DR EMBL; QJPL01000007; PXZ43140.1; -; Genomic_DNA.
DR RefSeq; WP_041504316.1; NZ_QJPL01000007.1.
DR AlphaFoldDB; A0A0C3RH27; -.
DR OrthoDB; 9780160at2; -.
DR Proteomes; UP000031980; Unassembled WGS sequence.
DR Proteomes; UP000248308; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR CDD; cd13133; MATE_like_7; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR43298:SF2; FMN_FAD EXPORTER YEEO-RELATED; 1.
DR PANTHER; PTHR43298; MULTIDRUG RESISTANCE PROTEIN NORM-RELATED; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000031980};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 9..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 50..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 158..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 49482 MW; 23E7C9D03AEC4DD1 CRC64;
MKTSISNKII WNIAYPIILG SLAQTLITLT DTAFLGRVSE IALGASAIAG IYYYVFSTLA
WGFSIGIQII VARRLGEGRL NRIGVVFEHG LFFVAFLGTS LFLVQHYFTK ELLETAIHSP
NIYAAAMEYM SFRHYGIIFV CFNFLYRALY IGLSNTKIIG YSTAVMATVN VLFNYLLIFG
KFGFPNLGVG GAALASVMAE ISAFLFFTLY TLLKLPLKQY ALFSFHKIEG WLMGTILKTA
LPTMLQKLLS FGTWFIFFIL VEHMGERPIA ITIVVRSVYM LIVIPVFGFG ATANTLTSRL
IGEQRQKEVM PMLTKVIRLS MLSVLPILAI CYLFPQQVLS IYSDSSELIQ ASVNSLYVVG
LAALALCFGI TFFEAISGTG NTSHALILET FVLILYTAQI WFLASVLQTS VESVWTVEVT
YGLCIGFISL LYMKHFRWQK HKL
//
