ID A0A0C4DL83_MAGP6 Unreviewed; 1122 AA.
AC A0A0C4DL83;
DT 01-APR-2015, integrated into UniProtKB/TrEMBL.
DT 01-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Nonsense-mediated mRNA decay factor {ECO:0000313|EMBL:KLU81434.1};
GN ORFNames=MAPG_00523 {ECO:0000313|EMBL:KLU81434.1};
OS Magnaporthiopsis poae (strain ATCC 64411 / 73-15) (Kentucky bluegrass
OS fungus) (Magnaporthe poae).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Magnaporthales; Magnaporthaceae; Magnaporthiopsis.
OX NCBI_TaxID=644358 {ECO:0000313|EnsemblFungi:MAPG_00523T0, ECO:0000313|Proteomes:UP000011715};
RN [1] {ECO:0000313|EMBL:KLU81434.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 64411 {ECO:0000313|EMBL:KLU81434.1};
RG The Broad Institute Genome Sequencing Platform;
RG Broad Institute Genome Sequencing Center for Infectious Disease;
RA Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Magnaporthe poae strain ATCC 64411.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000011715}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 64411 / 73-15 {ECO:0000313|Proteomes:UP000011715};
RA Ma L.-J., Dead R., Young S., Zeng Q., Koehrsen M., Alvarado L., Berlin A.,
RA Chapman S.B., Chen Z., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heilman E.R., Heiman D., Hepburn T., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Pearson M., Roberts A., Saif S., Shea T.,
RA Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C.,
RA Haas B., Nusbaum C., Birren B.;
RT "The genome sequence of Magnaporthe poae strain ATCC 64411.";
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:KLU81434.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 64411 {ECO:0000313|EMBL:KLU81434.1};
RA Ma L.-J., Dead R., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Brown A.,
RA Chapman S.B., Chen Z., Dunbar C., Freedman E., Gearin G., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Howarth C., Larson L., Lui A.,
RA MacDonald P.J.P., Mehta T., Montmayeur A., Murphy C., Neiman D.,
RA Pearson M., Priest M., Roberts A., Saif S., Shea T., Shenoy N., Sisk P.,
RA Stolte C., Sykes S., Yandava C., Wortman J., Nusbaum C., Birren B.;
RT "Annotation of Magnaporthe poae ATCC 64411.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EnsemblFungi:MAPG_00523T0}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 64411 / 73-15 {ECO:0000313|EnsemblFungi:MAPG_00523T0};
RX PubMed=26416668; DOI=10.1534/g3.115.020057;
RA Okagaki L.H., Nunes C.C., Sailsbery J., Clay B., Brown D., John T., Oh Y.,
RA Young N., Fitzgerald M., Haas B.J., Zeng Q., Young S., Adiconis X., Fan L.,
RA Levin J.Z., Mitchell T.K., Okubara P.A., Farman M.L., Kohn L.M., Birren B.,
RA Ma L.-J., Dean R.A.;
RT "Genome sequences of three phytopathogenic species of the Magnaporthaceae
RT family of fungi.";
RL G3 (Bethesda) 5:2539-2545(2015).
RN [5] {ECO:0000313|EnsemblFungi:MAPG_00523T0}
RP IDENTIFICATION.
RC STRAIN=ATCC 64411 {ECO:0000313|EnsemblFungi:MAPG_00523T0};
RG EnsemblFungi;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; ADBL01000122; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GL876966; KLU81434.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C4DL83; -.
DR STRING; 644358.A0A0C4DL83; -.
DR EnsemblFungi; MAPG_00523T0; MAPG_00523T0; MAPG_00523.
DR VEuPathDB; FungiDB:MAPG_00523; -.
DR eggNOG; KOG2051; Eukaryota.
DR OMA; DFQHHQI; -.
DR OrthoDB; 276824at2759; -.
DR Proteomes; UP000011715; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR Gene3D; 1.25.40.180; -; 3.
DR Gene3D; 4.10.80.160; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR InterPro; IPR039762; Nmd2/UPF2.
DR InterPro; IPR007193; Upf2/Nmd2_C.
DR PANTHER; PTHR12839; NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2; 1.
DR PANTHER; PTHR12839:SF7; REGULATOR OF NONSENSE TRANSCRIPTS 2; 1.
DR Pfam; PF02854; MIF4G; 2.
DR Pfam; PF04050; Upf2; 1.
DR SMART; SM00543; MIF4G; 2.
DR SUPFAM; SSF48371; ARM repeat; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000011715}.
FT DOMAIN 463..653
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT DOMAIN 668..875
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 169..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 246..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1079..1122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 422..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 923..944
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 945..968
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1122 AA; 126825 MW; FE09E74F5CC0D55D CRC64;
MDRARKRELR SLNDRAWAGE KDLIAVSSSL DSNMRKNSSF QKRLRTAISA TNLATFLQEI
RTLSLHKWLS ETVTACYDGL CRLKTPAEIE AGVEIVSALH QRFGPDEFTQ PLASHLAQAM
APPDKAKLKT MTAENREKDE RDRLMRQRVL IRVVTELWLV GVLRTLEDAA HPHDGTPKPA
PAGKPQDSKS RGTSGGAKPA SPEPFPLEVL KDLLGHDREH VNLPLLVAFV KAFSWDILGI
KAASADGRKA VEEDGATKLS SGGPDQDDDP PLTPPELQER FKNVLRRYFE DVKSHLERDQ
RAIFSQSRRN AEAYVKSGEV FEDRQANFDK QVKAQERLAA NAQVLADVIG AEMPDLKETG
DSLASANGSI GLVKTGEYLR GQGEGAGIWE DEDERRFYEN LVDLKGKVPA ILLEDVKKKK
PDAEEQVGKR VDAADAAEPP KPAADSVDDQ STAIANKTTG AQVDAILLRL PELTTKETID
QTAIDFCFLN SKASRNRLIK ALTDVPKGRS DLLPCWARLV ATLGQHMPDI PKGVVEYLDT
EFRSLQRRKD KDFLSQVRLS NIRYLAELTK FNIVPEHVVF HCLKVGLDDF SKMNIEVVCN
LLENCGRYLL RNPETSPRMS SFLETLQRKK SVQHIGQAER MLIENAIYYV NPPERPSIEQ
KERTPMELFV RKLVYVDLSK RNYSKVLKQI RRLHWEEAAV VSILMKVFSK PGRVKYGNIY
LLAILLGAIC KYHVDFAVTV IDNIIESIIF GLEQNEFKFN QRRIAEAKYL GELYNYRLFD
HPVVFDTMYK ILTFGHGGPP VPGRLNPFDL PDDFFRIRLI ATILETCGMF FNRGAQGKKL
DYFLSFFQYY IFTKDPLPMD IEFIVQDIYA LTRPQWKLAS NLEEASKAFQ LAITQDQKTS
GLDKAADQDD ASSGASSDEG EGDDLPIAVD DDEGDPEEDD LQNAERSDSE SRSESEDEAI
VVTRQEEELN PEDEAEFERE YAKMMAESID SRKFDRKPLF DVPLPVRPKM REASEGPAVN
APGTMAFSLL TKRGNRQQTR TVELPSDSHF AIAMKNQQQA EREEQQRIKN LVLNLDLGEN
ETDDGHYENK PSSYHHNRGE RQGKDRNAQR SRKLQLSDVD WT
//
