ID A0A0C4WHW6_9GAMM Unreviewed; 509 AA.
AC A0A0C4WHW6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=NADH-quinone oxidoreductase subunit M {ECO:0000256|ARBA:ARBA00019906};
DE AltName: Full=NADH dehydrogenase I subunit M {ECO:0000256|ARBA:ARBA00031584};
DE AltName: Full=NDH-1 subunit M {ECO:0000256|ARBA:ARBA00032798};
GN Name=nuoM {ECO:0000313|EMBL:AJE21378.1};
GN ORFNames=Achr_19230 {ECO:0000313|EMBL:AJE21378.1};
OS Azotobacter chroococcum NCIMB 8003.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Azotobacter.
OX NCBI_TaxID=1328314 {ECO:0000313|EMBL:AJE21378.1, ECO:0000313|Proteomes:UP000068210};
RN [1] {ECO:0000313|EMBL:AJE21378.1, ECO:0000313|Proteomes:UP000068210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 8003 {ECO:0000313|EMBL:AJE21378.1,
RC ECO:0000313|Proteomes:UP000068210};
RX PubMed=26061173;
RA Robson R.L., Jones R., Robson R.M., Schwartz A., Richardson T.H.;
RT "Azotobacter Genomes: The Genome of Azotobacter chroococcum NCIMB 8003
RT (ATCC 4412).";
RL PLoS ONE 10:E0127997-E0127997(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the complex I subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009025}.
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DR EMBL; CP010415; AJE21378.1; -; Genomic_DNA.
DR RefSeq; WP_039803871.1; NZ_CP010415.1.
DR AlphaFoldDB; A0A0C4WHW6; -.
DR STRING; 1328314.Achr_19230; -.
DR KEGG; acx:Achr_19230; -.
DR HOGENOM; CLU_007100_4_4_6; -.
DR Proteomes; UP000068210; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR010227; NADH_Q_OxRdtase_chainM/4.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR NCBIfam; TIGR01972; NDH_I_M; 1.
DR PANTHER; PTHR43507:SF1; NAD(P)H-QUINONE OXIDOREDUCTASE CHAIN 4, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43507; NADH-UBIQUINONE OXIDOREDUCTASE CHAIN 4; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000068210};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..431
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 509 AA; 55321 MW; 653E4DDBC873AF2B CRC64;
MILPWLILIP FIGGLLCWQG ERYSATLPRW IALLTMSLLL VLGLWLWATG DFTLAPAPEA
APLWSAEFRL SWIERFGIEL HLALDGLSML MVVLTGLLGV LSVLCSWKEI QQKVGFFHLN
LMWILGGVVG VFLAVDLFLF FFFWEMMLVP MYFLIALWGH SGSTGNTRIT AATKFFIFTQ
ASGLIMLVAI LGLVFVHYSQ SGVLTFNYAD LLKTQLAPGT EFLLMLGFFI SFAVKFPVIP
FHSWLPDAHA QAPTAGSVDL AGILLKTAAY GLLRFALPLF PNASAEFAPI AMGLGVFAIV
YGALVSFAQT DIKRLVAYSS VSHMGFILIA IYSGSQIALQ GAVVQMIAHG LSAAALFILC
GQLYERLHTR DMREMGGIWS RMPWLPAVSL FFAAAALGLP GTGNFVGEFL VLIGTFPQAP
WITVLASTGL VLGSVYSLIM IHRAYFGPAR TEGALLGLNG RELSMVLGLA GLLILLGVYP
QPVLDTSAAS MQGVQQWLST ALTQLVSAR
//
