ID A0A0C4YID9_9BURK Unreviewed; 327 AA.
AC A0A0C4YID9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=DNA polymerase I {ECO:0000313|EMBL:AJG22778.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:AJG22778.1};
GN ORFNames=RR42_s1190 {ECO:0000313|EMBL:AJG22778.1};
OS Cupriavidus basilensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=68895 {ECO:0000313|EMBL:AJG22778.1, ECO:0000313|Proteomes:UP000031843};
RN [1] {ECO:0000313|EMBL:AJG22778.1, ECO:0000313|Proteomes:UP000031843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4G11 {ECO:0000313|EMBL:AJG22778.1};
RX PubMed=25977418;
RA Ray J., Waters R.J., Skerker J.M., Kuehl J.V., Price M.N., Huang J.,
RA Chakraborty R., Arkin A.P., Deutschbauer A.;
RT "Complete Genome Sequence of Cupriavidus basilensis 4G11, Isolated from the
RT Oak Ridge Field Research Center Site.";
RL Genome Announc. 3:0-0(2015).
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DR EMBL; CP010537; AJG22778.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C4YID9; -.
DR STRING; 68895.RR42_s1190; -.
DR KEGG; cbw:RR42_s1190; -.
DR Proteomes; UP000031843; Chromosome secondary.
DR GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR CDD; cd09898; H3TH_53EXO; 1.
DR CDD; cd09859; PIN_53EXO; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR InterPro; IPR002421; 5-3_exonuclease.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR020045; DNA_polI_H3TH.
DR InterPro; IPR038969; FEN.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR Pfam; PF01367; 5_3_exonuc; 1.
DR Pfam; PF02739; 5_3_exonuc_N; 1.
DR SMART; SM00475; 53EXOc; 1.
DR SMART; SM00279; HhH2; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotidyltransferase {ECO:0000313|EMBL:AJG22778.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000031843};
KW Transferase {ECO:0000313|EMBL:AJG22778.1}.
FT DOMAIN 60..323
FT /note="5'-3' exonuclease"
FT /evidence="ECO:0000259|SMART:SM00475"
SQ SEQUENCE 327 AA; 36257 MW; C726ADD15EA79AC6 CRC64;
MLFISGRRLS LLRLDEADRR RNPAFLLILP TEKVARRASH VKIEGLIARI ARIARIARTM
KHTLLLIDGL NILRRVYEAN PAEDIPAKVE GAVLSALASF RRALTECKPT HALAAFDTGG
KTWRHALYPQ YRQHRKPMDP ELAEVLPDFR LTLTEVLGLQ TAMIEGYEAD DIIATAFYRW
TASKEGQVIP VSTDKDVLQL IADGAIVRNH FATAKNGEPS WFDERYVMDK FGVGSHQLAD
YLALLGDSTD DIPGVEKVGA KTAAKLLQRY GDLEGVLANA AEEKGVVGKN LAEQAHLARL
SRQLLSLKTD AQLGLTWNML RVGDTAE
//
