ID A0A0C4YUG7_9BURK Unreviewed; 271 AA.
AC A0A0C4YUG7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Spermidine synthase {ECO:0000313|EMBL:AJG24236.1};
DE EC=2.5.1.16 {ECO:0000313|EMBL:AJG24236.1};
GN ORFNames=RR42_s2654 {ECO:0000313|EMBL:AJG24236.1};
OS Cupriavidus basilensis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=68895 {ECO:0000313|EMBL:AJG24236.1, ECO:0000313|Proteomes:UP000031843};
RN [1] {ECO:0000313|EMBL:AJG24236.1, ECO:0000313|Proteomes:UP000031843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4G11 {ECO:0000313|EMBL:AJG24236.1};
RX PubMed=25977418;
RA Ray J., Waters R.J., Skerker J.M., Kuehl J.V., Price M.N., Huang J.,
RA Chakraborty R., Arkin A.P., Deutschbauer A.;
RT "Complete Genome Sequence of Cupriavidus basilensis 4G11, Isolated from the
RT Oak Ridge Field Research Center Site.";
RL Genome Announc. 3:0-0(2015).
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867}.
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DR EMBL; CP010537; AJG24236.1; -; Genomic_DNA.
DR RefSeq; WP_043356306.1; NZ_CP010537.1.
DR AlphaFoldDB; A0A0C4YUG7; -.
DR STRING; 68895.RR42_s2654; -.
DR KEGG; cbw:RR42_s2654; -.
DR OrthoDB; 117774at2; -.
DR Proteomes; UP000031843; Chromosome secondary.
DR GO; GO:0004766; F:spermidine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0008295; P:spermidine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; NF037959; MFS_SpdSyn; 1.
DR PANTHER; PTHR43317:SF12; POLYAMINE AMINOPROPYLTRANSFERASE; 1.
DR PANTHER; PTHR43317; THERMOSPERMINE SYNTHASE ACAULIS5; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|ARBA:ARBA00023115, ECO:0000256|PROSITE-
KW ProRule:PRU00354}; Reference proteome {ECO:0000313|Proteomes:UP000031843};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 70..227
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 147
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 271 AA; 29777 MW; 2599051403DC5722 CRC64;
MDPSRTSFEA YLKFLSEAPD DGTPTVLETP LALSLHFDAL ATQSIMSRHD PDKLVLGYTR
TMMAFLLLQP APARISMIGL GGGSLLKYCY RHLPQAKVVA IEIDPAVIAL RDTFHIPPDD
ERLEVVCADG AEYVKSQDAR PEVILVDGFL AHGMPAQLGN AAFYAACHAR LADDGVLVAN
YLDSDADIPF YLEEIRSVFG ESFSIALSED SCNYTLFAWK GARALPSQDE LLTRARALEA
THPLNLRAAA RRLKQGKRLA SDHTFWQKLA G
//
