ID A0A0C5FN62_9ACTN Unreviewed; 254 AA.
AC A0A0C5FN62;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:AJP01257.1};
GN ORFNames=TU94_06970 {ECO:0000313|EMBL:AJP01257.1};
OS Streptomyces cyaneogriseus subsp. noncyanogenus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=477245 {ECO:0000313|EMBL:AJP01257.1, ECO:0000313|Proteomes:UP000032234};
RN [1] {ECO:0000313|EMBL:AJP01257.1, ECO:0000313|Proteomes:UP000032234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NMWT 1 {ECO:0000313|EMBL:AJP01257.1,
RC ECO:0000313|Proteomes:UP000032234};
RA Wang H., Li C., Xiang W., Wang X.;
RT "Genome sequence of thermotolerant Streptomyces cyaneogriseus subsp.
RT Noncyanogenus NMWT1, the producer of nematocidal antibiotics nemadectin.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP010849; AJP01257.1; -; Genomic_DNA.
DR RefSeq; WP_044380408.1; NZ_CP010849.1.
DR AlphaFoldDB; A0A0C5FN62; -.
DR STRING; 477245.TU94_06970; -.
DR KEGG; scw:TU94_06970; -.
DR PATRIC; fig|477245.3.peg.1506; -.
DR HOGENOM; CLU_062618_6_2_11; -.
DR OrthoDB; 4474604at2; -.
DR Proteomes; UP000032234; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032234};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 5..67
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 68..251
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 254 AA; 27572 MW; 10AC3ED355D09704 CRC64;
MARNIQSLER AAAMLRLLAG GERRLGLSDI ASSLGLAKGT AHGILRTLQH EGFVEQDDAS
GRYQLGAELL RLGTTYLDVH ELRARALVWA DDLARSSGES VHLGVLHQQG VLIVHHVFRP
DDSRQVLEIG AMQPLHSTAL GKVLAAYDPV ARSEAVESER KAFTDRTVCD PDGFEQILDL
TRARGYAADV EETWEGVASI AAPIHDRRRM PVGAVGITGA VERLCRDGEL RPELVAAVRD
CARAVSRDLG AGRF
//
