ID A0A0C5FYD7_9ACTN Unreviewed; 354 AA.
AC A0A0C5FYD7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Stilbene synthase {ECO:0000313|EMBL:AJP00909.1};
GN ORFNames=TU94_04905 {ECO:0000313|EMBL:AJP00909.1};
OS Streptomyces cyaneogriseus subsp. noncyanogenus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=477245 {ECO:0000313|EMBL:AJP00909.1, ECO:0000313|Proteomes:UP000032234};
RN [1] {ECO:0000313|EMBL:AJP00909.1, ECO:0000313|Proteomes:UP000032234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NMWT 1 {ECO:0000313|EMBL:AJP00909.1,
RC ECO:0000313|Proteomes:UP000032234};
RA Wang H., Li C., Xiang W., Wang X.;
RT "Genome sequence of thermotolerant Streptomyces cyaneogriseus subsp.
RT Noncyanogenus NMWT1, the producer of nematocidal antibiotics nemadectin.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
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DR EMBL; CP010849; AJP00909.1; -; Genomic_DNA.
DR RefSeq; WP_044379603.1; NZ_CP010849.1.
DR AlphaFoldDB; A0A0C5FYD7; -.
DR STRING; 477245.TU94_04905; -.
DR KEGG; scw:TU94_04905; -.
DR PATRIC; fig|477245.3.peg.1078; -.
DR HOGENOM; CLU_034992_0_1_11; -.
DR OrthoDB; 9786288at2; -.
DR Proteomes; UP000032234; Chromosome.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000032234}.
FT DOMAIN 13..203
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 218..353
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 144
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 354 AA; 37782 MW; 67A6E4AFFB477401 CRC64;
MRGTRPGRTG PRLVAVGSAT PPTSYTQQEL LEIFRVEDPR IRSLFLNGGI QRRYLTLPPE
LPDGTRLAET QGDLLAKHLT SGVSIGTEAV QKCLKEARAD VGDIGYLCCV SSTGFLTPGF
SALLVKELGI PVTCSRLDVV GMGCNAGLNA LAAVSGWATA NPGRLAVMVC VEVCSAAYVF
DGTMRTSVVN SLFGDGAAAL ALTSGGDTGP EITGFASRII PEAVDAMRYD WDEQQGRFSF
FLDQDIPYVV GAHAERAVGR LLAQAGLRRS DIDHWVIHSG GKKVIDAVRI NLGLTRHDTR
HTTDVLRDCG NLSSGAFLFS YQRLLEEAVV APGDNGVLMT MGPGSTIETA LLRW
//
