ID A0A0C5G527_9ACTN Unreviewed; 491 AA.
AC A0A0C5G527;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=TU94_21860 {ECO:0000313|EMBL:AJP03735.1};
OS Streptomyces cyaneogriseus subsp. noncyanogenus.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=477245 {ECO:0000313|EMBL:AJP03735.1, ECO:0000313|Proteomes:UP000032234};
RN [1] {ECO:0000313|EMBL:AJP03735.1, ECO:0000313|Proteomes:UP000032234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NMWT 1 {ECO:0000313|EMBL:AJP03735.1,
RC ECO:0000313|Proteomes:UP000032234};
RA Wang H., Li C., Xiang W., Wang X.;
RT "Genome sequence of thermotolerant Streptomyces cyaneogriseus subsp.
RT Noncyanogenus NMWT1, the producer of nematocidal antibiotics nemadectin.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; CP010849; AJP03735.1; -; Genomic_DNA.
DR RefSeq; WP_044383731.1; NZ_CP010849.1.
DR AlphaFoldDB; A0A0C5G527; -.
DR STRING; 477245.TU94_21860; -.
DR KEGG; scw:TU94_21860; -.
DR PATRIC; fig|477245.3.peg.4617; -.
DR HOGENOM; CLU_045351_1_0_11; -.
DR OrthoDB; 9767435at2; -.
DR Proteomes; UP000032234; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.450.280; GAF domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR022066; PdtaS_GAF.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR43065:SF23; SENSOR HISTIDINE KINASE PDTAS-RELATED; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12282; PdtaS_GAF; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032234}.
FT DOMAIN 293..489
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 491 AA; 54130 MW; 9B3C17807C0676FD CRC64;
MPSMNELVRQ HTALDDSDLE WLHLLVSEWQ LLSDLSFADL VLWVPTRDGT RYVSVAQMRP
NTGPTSYQDD MVGHLVPRGR RPMLDVALDE GRIVREGDPE WREEVPVRVE SIPVRRQGRV
LGVIARNTNL LTVRTPSRLE LTYLQSASDL AQMIAAGAFP FENQQVDMDA SPRVGDGLIR
LDADGIVQYA SPNALSAYHR LGLAADLVGH HLGRTTAELA PSRGPVDEAL AKVASGWAPR
EFEIEAHDGV IQFRAIPLKP KGTRIGSLVL LRDVTELRRR ERELITKDAT IREIHHRVKN
NLQTVAALLR LQARRIGSDR GREALEEAVR RVGSIAIVHE TLSQNLDERV EFDDIADRVL
AMVAEISPGK VTGRRTGRFG ILDAEVATPL SMVLTEILQN ALEHGFREGD TGTVEVAAVR
GGTTKEARLL VTVQDDGVGL PEDFDPHRSG NLGLQIVRTL VEGELGGTFD MVPAPGHGTR
VILDIPVRAQ K
//
