ID A0A0C5V4G5_9GAMM Unreviewed; 648 AA.
AC A0A0C5V4G5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Zn-dependent protease with chaperone function {ECO:0000313|EMBL:AJQ94370.1};
GN ORFNames=YC6258_02332 {ECO:0000313|EMBL:AJQ94370.1};
OS Gynuella sunshinyii YC6258.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Gynuella.
OX NCBI_TaxID=1445510 {ECO:0000313|EMBL:AJQ94370.1, ECO:0000313|Proteomes:UP000032266};
RN [1] {ECO:0000313|EMBL:AJQ94370.1, ECO:0000313|Proteomes:UP000032266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC6258 {ECO:0000313|EMBL:AJQ94370.1,
RC ECO:0000313|Proteomes:UP000032266};
RA Khan H., Chung E.J., Chung Y.R.;
RT "Full genme sequencing of cellulolytic bacterium Gynuella sunshinyii
RT YC6258T gen. nov., sp. nov.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP007142; AJQ94370.1; -; Genomic_DNA.
DR RefSeq; WP_044616906.1; NZ_CP007142.1.
DR AlphaFoldDB; A0A0C5V4G5; -.
DR STRING; 1445510.YC6258_02332; -.
DR KEGG; gsn:YC6258_02332; -.
DR PATRIC; fig|1445510.3.peg.2288; -.
DR HOGENOM; CLU_024494_0_0_6; -.
DR OrthoDB; 15218at2; -.
DR Proteomes; UP000032266; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07340; M48B_Htpx_like; 1.
DR Gene3D; 3.30.2010.10; Metalloproteases ('zincins'), catalytic domain; 1.
DR InterPro; IPR001915; Peptidase_M48.
DR PANTHER; PTHR43221; PROTEASE HTPX; 1.
DR PANTHER; PTHR43221:SF2; PROTEASE HTPX HOMOLOG; 1.
DR Pfam; PF01435; Peptidase_M48; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:AJQ94370.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 17..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..89
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 114..337
FT /note="Peptidase M48"
FT /evidence="ECO:0000259|Pfam:PF01435"
SQ SEQUENCE 648 AA; 72771 MW; A193A07E968886E6 CRC64;
MDFFEHQDRA RRNTWKLILF FVTATLLIVM AVNALAFTVW LSWQNHTSYP HLSIPLGFQQ
WLNNPNAWFT AGATILILLS GSLLQWLNLA KGGEAVARMA DARPIEEFFN DPKATQFRNV
VAEMAIASGV SAPKLYIMDR ETGINAFVAG YQVNQAVMVV TRGMLTHLNR EQIQGVVGHE
FSHILNGDMR LNIRLMSMLA GIVMIGQFGR FMADIGGRSG YRSRRSRNNN SALPVFLAGL
ALMAIGAIGV FFGRLIRAAV SRQREFLADA SSVQFTRNPE AVAGALYKIQ KQSEGSLLQH
RHAEDMSHFC FGNTVHIAHF NHLLATHPPL PERIKRIAPN FLARQRNIEN RDLENTPQQN
QAPEATLIGG MAAAVTGLQI QQVVGQTSAA HVDYAHQLYK QIPPYVRTLL ATSAGARAFC
YGVILKENDQ QQEIVRFIAS EDPNGAENLA RLWKWQRQAA PALRLPCLEL CIPALNKHTV
EDILIFLQRI QRLCEWDQQI VLMEWIVLSL LDHHLNPAHK TRDKVKHHSL KNLGEELQLL
LSSLVYLNTD LQKANNAYKQ AMTSMGFADR WLLSRTAIPL TRLQPVMTEL NGLSFILKKT
VIQACSDIIL SDQQVNVSEY DCLRTIATVF GCPMPPLILE KEQLFGVH
//
