ID   A0A0C5VRW9_9GAMM        Unreviewed;      1007 AA.
AC   A0A0C5VRW9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Alpha-mannosidase {ECO:0000313|EMBL:AJQ96976.1};
DE            EC=3.2.1.24 {ECO:0000313|EMBL:AJQ96976.1};
GN   ORFNames=YC6258_04944 {ECO:0000313|EMBL:AJQ96976.1};
OS   Gynuella sunshinyii YC6258.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Saccharospirillaceae; Gynuella.
OX   NCBI_TaxID=1445510 {ECO:0000313|EMBL:AJQ96976.1, ECO:0000313|Proteomes:UP000032266};
RN   [1] {ECO:0000313|EMBL:AJQ96976.1, ECO:0000313|Proteomes:UP000032266}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YC6258 {ECO:0000313|EMBL:AJQ96976.1,
RC   ECO:0000313|Proteomes:UP000032266};
RA   Khan H., Chung E.J., Chung Y.R.;
RT   "Full genme sequencing of cellulolytic bacterium Gynuella sunshinyii
RT   YC6258T gen. nov., sp. nov.";
RL   Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
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DR   EMBL; CP007142; AJQ96976.1; -; Genomic_DNA.
DR   RefSeq; WP_044618856.1; NZ_CP007142.1.
DR   AlphaFoldDB; A0A0C5VRW9; -.
DR   STRING; 1445510.YC6258_04944; -.
DR   KEGG; gsn:YC6258_04944; -.
DR   PATRIC; fig|1445510.3.peg.4904; -.
DR   HOGENOM; CLU_003442_1_0_6; -.
DR   OrthoDB; 9764050at2; -.
DR   Proteomes; UP000032266; Chromosome.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000313|EMBL:AJQ96976.1};
KW   Hydrolase {ECO:0000313|EMBL:AJQ96976.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032266}.
FT   DOMAIN          517..593
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1007 AA;  113321 MW;  76E0C7C935BF5A79 CRC64;
     MVHSLTLQQR LERHQVRLEE LVYWTERQKQ PLTQLTLEGE PATVGTPWPG TDGVFNFTGN
     GTVPADWPLA DCRLRMNLGG EGLVMLSDDQ GIATGYGIDP YHRSFPLKSC QFSFTAECTA
     RLPFGEPVRA PRIEWAELVW IDTAVEQLHL LMQQIAEAAE TLKGHDVVPH LLDLAEKAFY
     QLDWPSATEH YISRTAQAPL QQKIWQLPVT RGEPSELSEQ QRQTVIDVYQ QLLKGLAELQ
     KRFPPEGEIA LTGHAHIDLC WLWPYDETRR KLRRTFHTAL SLMEQSPEFR FNQSTAHYYW
     QISQTDPALL EKITERVKTG QWETLGGLWV EPDTNMPTGE SLARQVLYGQ QFFEQQFGIR
     HETCWMPDCF GFTGALPQLL QQGGMKNFFT IKVNWSETNR FPADLFWWEG LDGSRVLMHT
     FDNPMQGYNG FVHPHGHRET WKNFRGKDKH PQTLLTVGYG DGGGGPVPEM ITREEQLKVF
     PTLPKARWAT VKDFFAGANQ SAERTALPVW AGEIYLELHR ATLTTQGRVK KAHRDAEQAL
     ISAEIAGSLA HMLGADAPDS LRDSWRYVLK NEFHDILPGS SIREVNIQAV EELTEVIRQA
     HEYQQDAMQT LIGQLPAAHG KHLVVVNPSL DCRPLETELA DGTALSTDTL LPPLSVAVVD
     PDQLQPGGSL SVSETHLENR HLRILLNADG TLASMLHKAS GRETLAGRGN QLWAYTADKP
     RNWDAWDVEE DFAARGEEIT DLHSLQVVES GSHRVAIRLV RQFRDSRICQ TYSLTANGKR
     LDIHTELDWH DRRILLKTLT PVAVKAREAT CECAYGVVKR PTHENTSWDA AMFEAAAHRF
     ADLSEPGFGV ALLNNGKYGH SIRHNILALS LLRSPIYPDP LADEGEQQFT YALYPHNDEW
     YRGGVREEAE ALNRPLLISE SQPAAMGLYQ PVKLSGPVSL SGFKPAEDGQ GLILRVYEPA
     GGRGSLEMGL TKGWKNEGPV TVLEEPMNVS ANSIKPFEIK SFRLCRG
//