ID A0A0C5W3M1_9GAMM Unreviewed; 577 AA.
AC A0A0C5W3M1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=NhaP-type Na+/H+ and K+/H+ antiporter with a unique C-terminal domain {ECO:0000313|EMBL:AJQ97219.1};
GN ORFNames=YC6258_05189 {ECO:0000313|EMBL:AJQ97219.1};
OS Gynuella sunshinyii YC6258.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Saccharospirillaceae; Gynuella.
OX NCBI_TaxID=1445510 {ECO:0000313|EMBL:AJQ97219.1, ECO:0000313|Proteomes:UP000032266};
RN [1] {ECO:0000313|EMBL:AJQ97219.1, ECO:0000313|Proteomes:UP000032266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YC6258 {ECO:0000313|EMBL:AJQ97219.1,
RC ECO:0000313|Proteomes:UP000032266};
RA Khan H., Chung E.J., Chung Y.R.;
RT "Full genme sequencing of cellulolytic bacterium Gynuella sunshinyii
RT YC6258T gen. nov., sp. nov.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP007142; AJQ97219.1; -; Genomic_DNA.
DR RefSeq; WP_044619016.1; NZ_CP007142.1.
DR AlphaFoldDB; A0A0C5W3M1; -.
DR KEGG; gsn:YC6258_05189; -.
DR PATRIC; fig|1445510.3.peg.5153; -.
DR HOGENOM; CLU_005912_9_2_6; -.
DR OrthoDB; 9810759at2; -.
DR Proteomes; UP000032266; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR32507:SF7; K(+)_H(+) ANTIPORTER NHAP2; 1.
DR PANTHER; PTHR32507; NA(+)/H(+) ANTIPORTER 1; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022538};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000032266};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022449}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 30..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 278..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..325
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 406..487
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 577 AA; 62014 MW; C50492998B09C444 CRC64;
MTIELTYQYI FGAAILALLC VVASAVTRRV GAPVLLVFLV LGMLAGEDGP GGIRFDDFNL
AFLFGNVALA VIIFDGGLGT RKDTFRVSLK PALSLATVGV LLTAAITGFA AYLILGLSWQ
EGLLIGAIVG STDAAAVFGL LGSAGFELKE RTGATLEIES GSNDPMAIFL TITLVQVLHL
ESQGNQGWTI ASELVRQMGL GLAVGFTGGY LLVRALQYLS LPATLYPLLA LAGGISLFGV
TTIWQGSGFL AIYIAGVMIG NASLSYSKDI HRFHDGMAWL SQIGMFLMLG LLITPTHMVP
VILPALGVAA VLIFIARPLA VIVSLLPFHF PWREQAFISW CGLRGAVPII LALFPSLAGL
EHTQIYFELV FFVVLVSLVI QGWTIAPVAK WLQVALPPTT VEPEFLHVLI KGEHDKELLV
YPVGKGSHAE GSIIGRLLLE EGSQVVGVIR QGVLLQNTPK QKLSGDDTVV ILATDRSRQS
LSRFFAPSSQ DQQLESGHFF GEFVLRPDAR LAEIAHTYGF SIEPVDTDLT VAEYIARQFH
DKPVVGDQVR LGLVSLIVRE TDGNHIISVG LKLRPKP
//
