ID A0A0C5WV71_9GAMM Unreviewed; 456 AA.
AC A0A0C5WV71;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Melibiose:sodium symporter {ECO:0000313|EMBL:AJR08974.1};
GN ORFNames=H744_2c2311 {ECO:0000313|EMBL:AJR08974.1};
OS Photobacterium gaetbulicola Gung47.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=658445 {ECO:0000313|EMBL:AJR08974.1, ECO:0000313|Proteomes:UP000032303};
RN [1] {ECO:0000313|EMBL:AJR08974.1, ECO:0000313|Proteomes:UP000032303}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gung47 {ECO:0000313|EMBL:AJR08974.1,
RC ECO:0000313|Proteomes:UP000032303};
RA Kim Y.-O.;
RT "Complete genome sequence of the lipase-producing bacterium Photobacterium
RT gaetbulicola Gung47.";
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC family. {ECO:0000256|ARBA:ARBA00009617}.
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DR EMBL; CP005974; AJR08974.1; -; Genomic_DNA.
DR RefSeq; WP_044623559.1; NZ_CP005974.1.
DR AlphaFoldDB; A0A0C5WV71; -.
DR STRING; 658445.H744_2c2311; -.
DR KEGG; pgb:H744_2c2311; -.
DR PATRIC; fig|658445.3.peg.4306; -.
DR HOGENOM; CLU_027408_0_3_6; -.
DR OrthoDB; 181905at2; -.
DR Proteomes; UP000032303; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR CDD; cd17332; MFS_MelB_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR039672; MFS_2.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR001927; Na/Gal_symport.
DR InterPro; IPR018043; Na/Gal_symport_CS.
DR NCBIfam; TIGR00792; gph; 1.
DR PANTHER; PTHR11328; MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11328:SF36; MELIBIOSE PERMEASE; 1.
DR Pfam; PF13347; MFS_2; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032303};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 456 AA; 49410 MW; FBAD7CF21C6370AC CRC64;
MSDKITLQTK LSYGLGALGK DFACAPIYIF LMFYFTDVAG LSAAFVGTIF LAARIIDAVT
DPMMGVIVDN TRSKFGKFRP WIVIGTLLNA IVLVGLFSTH MFEGPALYLY AAAAYILWGL
TYTIMDIPYW SMIPALSSER QEREKLVVWP RLFASLAWFI TGTYGLHIVG VLGDGNQGDG
FFNVAMLIAV LFVMSAFLIA RNVKEKAAPA NAKAAEKFSF KDVLVIIGKN DQLKALIGTV
LSFQIANLLV GGFAIYYFSY ALGNPELFPV YMMVAGAAEV AGVFLFPRIA AKLPRKHLWK
MACGFPILSC VVLLVMGVMF PGNAFLIGLA GAAIKFGVGI ANALQTVMLA DVVDYGEYKT
GRRSESVIFS VQTMLVKFAG AAGGFIVGVG LSVVGYVPNV EQTADTIMGL HFMMVGLPAI
LMAVSGFVYQ RYYRLHDGFN KDEVETAAVN AKPVEA
//
