ID   A0A0C7N1D9_9SACH        Unreviewed;       346 AA.
AC   A0A0C7N1D9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=LALA0S04e00496g1_1 {ECO:0000313|EMBL:CEP61781.1};
GN   ORFNames=LALA0_S04e00496g {ECO:0000313|EMBL:CEP61781.1};
OS   Lachancea lanzarotensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1245769 {ECO:0000313|EMBL:CEP61781.1, ECO:0000313|Proteomes:UP000054304};
RN   [1] {ECO:0000313|EMBL:CEP61781.1, ECO:0000313|Proteomes:UP000054304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 12615 {ECO:0000313|EMBL:CEP61781.1,
RC   ECO:0000313|Proteomes:UP000054304};
RA   Neuveglise Cecile;
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000256|ARBA:ARBA00004406}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004406}.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219}.
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DR   EMBL; LN736363; CEP61781.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C7N1D9; -.
DR   STRING; 1245769.A0A0C7N1D9; -.
DR   HOGENOM; CLU_007383_6_8_1; -.
DR   OrthoDB; 1133at2759; -.
DR   Proteomes; UP000054304; Unassembled WGS sequence.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   CDD; cd09813; 3b-HSD-NSDHL-like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054304}.
FT   DOMAIN          6..277
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
SQ   SEQUENCE   346 AA;  38042 MW;  119B0BB3D430E78C CRC64;
     MRSVLLVGGS GFLGLHLVEK FYNLSPRPEI HVFDVRPLPE KLSKAFTFDP KKIKVHVGDL
     TSESDISEAL RSSHADIVVH SASPMHGCSQ EIYDKVNVEG TKNLLSVSKH MGVKAFVYTS
     SAGVIFNGQD IHNADESWPI PEVPMDGYNE TKATAEAMVL RANSANESFF TLALRPAGIF
     GPGDRQLVPG LRNVAKMGQS KFQIGDNNNL FDWTYVGNVA DAHVLAAEKL LDTSACPTVA
     AQSFFITNDA PTYFWALART VWRADGHVDS YNIVLPRPLA IAVGYLSEYF SKFTGKEPGL
     TPFRVKIVCA YRYHNISKAK SLLGYIPNVD IEDGIAKTLS WMDEAI
//