ID   A0A0C7N4D9_9SACH        Unreviewed;       622 AA.
AC   A0A0C7N4D9;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Autophagy-related protein 20 {ECO:0000256|ARBA:ARBA00039251};
GN   ORFNames=LALA0_S03e03708g {ECO:0000313|EMBL:CEP61476.1};
OS   Lachancea lanzarotensis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=1245769 {ECO:0000313|EMBL:CEP61476.1, ECO:0000313|Proteomes:UP000054304};
RN   [1] {ECO:0000313|EMBL:CEP61476.1, ECO:0000313|Proteomes:UP000054304}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 12615 {ECO:0000313|EMBL:CEP61476.1,
RC   ECO:0000313|Proteomes:UP000054304};
RA   Neuveglise Cecile;
RL   Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}. Preautophagosomal structure membrane
CC       {ECO:0000256|ARBA:ARBA00004623}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004623}.
CC   -!- SIMILARITY: Belongs to the sorting nexin family.
CC       {ECO:0000256|ARBA:ARBA00010883}.
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DR   EMBL; LN736362; CEP61476.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C7N4D9; -.
DR   STRING; 1245769.A0A0C7N4D9; -.
DR   HOGENOM; CLU_014456_2_1_1; -.
DR   OrthoDB; 5475877at2759; -.
DR   Proteomes; UP000054304; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:UniProt.
DR   GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   CDD; cd06867; PX_SNX41_42; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR044106; PX_Snx41/Atg20.
DR   PANTHER; PTHR46979:SF1; AUTOPHAGY-RELATED PROTEIN 20; 1.
DR   PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS50195; PX; 1.
PE   3: Inferred from homology;
KW   Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054304}.
FT   DOMAIN          125..286
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          68..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          116..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   622 AA;  69894 MW;  4C8D136B49BBE33C CRC64;
     MDKMAPTEES RNHNDLESRV NESSVLIDVK RVLGEIENGA TEQAAFEEPT PLESDAQAVS
     MVHTEIFEQD NPFSGQQARR GETNGTGLKD QKRVLQNPNK VFEDDDDGAP MLLGHGTRSS
     SSGSIEMSPA ASDNVDRGVR RPGDEVYILE ASKASEGQGR TFIAYTIKHG DATVRRRYSD
     FESLRKILIK LFPMTLIPPI PEKQSITSFG RAMAGSKSSY LLPSETAGSV DLSLSVINGA
     VNTNDEKLIR HRIRMLTSFL NRLLRNEEIT KTSIVSDFLD PNNSNWNDVI TSSATISSLP
     KSVLLCNPLD PTNTTRAHAF LPIPSSSTQL LLNKELLANS AQDDTEDGFS KIEQEYRRYE
     HIMENGFYKY NKRITKNLYA MRQDMKELSE AFAAFSNDQK RGAELAEQLS HLSNVFDESS
     LELESVVGKL YYNINEPLSE AVHMAGAAQE LLRYRKLKSM QKSILSRTLL YRKAQLKKLQ
     EKETEAKKID AFVEQQLAGS EHVNLKHPEA RSYSGKLMNK INKLATMVKD TVNYQESDPA
     TAIENLEKDI AQLSESLDVS ERDLDTISTT IKNFELPKFC TSRNSEVSEI LKNYSRYLKA
     HAEKNLKIWK DVKEQQGNVS RS
//