ID A0A0C7P3G3_DEFTU Unreviewed; 392 AA.
AC A0A0C7P3G3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:CEP78830.1};
GN Name=nhaP {ECO:0000313|EMBL:CEP78830.1};
GN ORFNames=DTL3_1540 {ECO:0000313|EMBL:CEP78830.1};
OS Defluviitoga tunisiensis.
OC Bacteria; Thermotogota; Thermotogae; Petrotogales; Petrotogaceae;
OC Defluviitoga.
OX NCBI_TaxID=1006576 {ECO:0000313|EMBL:CEP78830.1, ECO:0000313|Proteomes:UP000032809};
RN [1] {ECO:0000313|Proteomes:UP000032809}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L3 {ECO:0000313|Proteomes:UP000032809};
RA Wibberg D.;
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; LN824141; CEP78830.1; -; Genomic_DNA.
DR RefSeq; WP_045088202.1; NZ_LN824141.1.
DR AlphaFoldDB; A0A0C7P3G3; -.
DR STRING; 1006576.DTL3_1540; -.
DR KEGG; dtn:DTL3_1540; -.
DR PATRIC; fig|1006576.9.peg.1537; -.
DR HOGENOM; CLU_031031_2_1_0; -.
DR OrthoDB; 2758at2; -.
DR Proteomes; UP000032809; Chromosome I.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR43021; NA(+)/H(+) ANTIPORTER-RELATED; 1.
DR PANTHER; PTHR43021:SF2; NA_H_EXCHANGER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032809};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..135
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..377
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 392 AA; 41535 MW; 02C73407A6324A1B CRC64;
MHMLFYVSVI LLTGLVMAKV IRLLKLPNVT GYLLGGLLIG PSVLGIIPRD VVGSFSIISE
AALAFIAYSI GSELNIEHLK KIGKGVVLIT FLEAIGATLC VTLGMIFIFR QPVHLSIVLG
AIGSATAPAA TLMVVKQYNA KGPLVDTLLP VVAMDDAVCI MIFGIASAIA KILLEGVESV
SLASLILSPI FEIIGALALG FFMGFILAWI SKKVKGEDEL LSVIIAFIFL TTGLSIQFNF
SSLLSCMMLG TTLTNILPHN KRVFTVIEHF TPPLLVLFFT ISGVELNLSI LKSVGLIGIA
YVVLRAVGKM LGGYLGAAAA KSPKTVRNYL GFALLPQAGV AIGLSMVAQR ILPAPYGDEI
RTVILAAVII YELIGPPLAK FALVKAGEIQ SE
//
