ID A0A0C9LPR2_9FUNG Unreviewed; 817 AA.
AC A0A0C9LPR2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Low temperature essential 1 protein {ECO:0000313|EMBL:GAN00980.1};
GN ORFNames=MAM1_0004d00408 {ECO:0000313|EMBL:GAN00980.1};
OS Mucor ambiguus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN00980.1};
RN [1] {ECO:0000313|EMBL:GAN00980.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN00980.1};
RA Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT ambiguus NBRC6742.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; DF836293; GAN00980.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9LPR2; -.
DR STRING; 91626.A0A0C9LPR2; -.
DR OrthoDB; 5476208at2759; -.
DR Proteomes; UP000053815; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF364; GUANINE NUCLEOTIDE EXCHANGE FACTOR LTE1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053815}.
FT DOMAIN 233..360
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 523..812
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
SQ SEQUENCE 817 AA; 94239 MW; CB9E2B05F5EB7B4F CRC64;
MLGITAEYDT FFAKSNYRRR SKSLDDIIIR KKGDRLSCYQ DTITSTSPIV AIHDLPPKRR
HSVHEPHQRL ATIYGWVTTA KPSHSSHESN RRLHASRSFS HFSAAAVEEE AGMSLPDPTT
NKLSRMLERT RNISLLFPNK TITGINNDKS HSHYYHHRQH VDQILLDPMQ QQHEHGESWV
QPESTVQTLT SPQQSVAAVA AENRPPPLPI ENDPHIFDLL AKDASSFIHY GKSDAIITSA
TVEKLIEKLT REMDNEFMMD FFLTFRQFLT PIKLCKLLIL RFRWALLQED DERRLIRIRT
FVVIRHWLTH YWTYDFTTSR TLRYVLSTFL TQLQSNPVIL ASPRDDRIVK NLRNVLKRQR
KFYQQWVDPL QQQEPDEKGK LPSRKDSAIG ISSCRNSLHL NQQDNGTHSS TPVPSLSSWT
TKMKKSLKRT VSIRQPQSNA TGQPPTLYST VNNAPCSCHL TDCSLSTASS VSLSNIQHKE
PCTMHPSLTR PSPALHTPSR FFRTSNASTA TLSHYKSIIL KYRSEVIAQQ FCLIERAMLQ
NVTWDELVDL RWRKRSAQRK SFVIEMTTLD DDVPVGVDQM IGFFNMTCQW VASEIVQSQQ
LDTRVKVIEK FLRIALKCYH HRNYSTLMQI LLGLQSPAVS RLERTWQKLD HCQMELFNQL
KEMAKPFRNW KNVRDCMTKA TEEVAESFAV ESVLTKSLKE FDNSHGCIPF LGLYLSDLVF
VAELPTFIGS ALPEDGEQEE EQEQQSDDKD LCERLSHHLV NYNKFRITAS VVKHVLAFQV
LSRAYNFKVH PTLHTHLRSI RSLDNADIRK ASFLCEE
//
