ID   A0A0C9MSB6_9FUNG        Unreviewed;       572 AA.
AC   A0A0C9MSB6;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN   ORFNames=MAM1_0115d05682 {ECO:0000313|EMBL:GAN06202.1};
OS   Mucor ambiguus.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX   NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN06202.1};
RN   [1] {ECO:0000313|EMBL:GAN06202.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN06202.1};
RA   Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT   "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT   ambiguus NBRC6742.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC       known as the alpha DNA polymerase-primase complex) which plays an
CC       essential role in the initiation of DNA synthesis.
CC       {ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR018300}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC       {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
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DR   EMBL; DF836404; GAN06202.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0C9MSB6; -.
DR   STRING; 91626.A0A0C9MSB6; -.
DR   OrthoDB; 49016at2759; -.
DR   Proteomes; UP000053815; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.21.60; -; 2.
DR   InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR   InterPro; IPR016722; DNA_pol_alpha_bsu.
DR   InterPro; IPR013627; Pol_alpha_B_N.
DR   PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR   PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR   Pfam; PF04042; DNA_pol_E_B; 1.
DR   Pfam; PF08418; Pol_alpha_B_N; 1.
DR   PIRSF; PIRSF018300; DNA_pol_alph_2; 1.
PE   3: Inferred from homology;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW   ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053815}.
FT   DOMAIN          17..228
FT                   /note="DNA polymerase alpha subunit B N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08418"
FT   DOMAIN          324..528
FT                   /note="DNA polymerase alpha/delta/epsilon subunit B"
FT                   /evidence="ECO:0000259|Pfam:PF04042"
SQ   SEQUENCE   572 AA;  64903 MW;  476675AF58D2CD16 CRC64;
     MSDIKQLFSL GNNTDDQEVA TELLSLCTIY TITPEVLRNK WEAFALTTGC ALKPSLPYVK
     HLKNSLQREF DRQLKKQKTS RGAVVTKKPR MDLSDYGINT DTQDDSVESF MSNMFSSSNA
     RPTKIMPMTP SASLNDTQIS QVSSQFLTRK SAHVMDGQYN PHLPLRGDYI EDKPVIFNHL
     QDPIKPYRFM YEKTREKADM MDEHIDYIGS LIKEYHNIEA FANPARASQE PIYAYGRICP
     DASEGRLNDQ SVLLQLSRDV GMGKRVKLNL AKVSDYSLFP GQIVGVFGTN MRGDVFHVDQ
     FLLPPMPNNI ESDVLTDRKP VEMIVASGPY TLDDDLSYQP LEDLLKKCEQ DQPNVILLMG
     PFISANHPRV ASGKIESLPE EVFHNQIVKR LEQFLEKSLH SHVLLMPHAD DMIHSFPLYP
     QPPLENTIRH GRLHQLSNPA QISINGHNIS ASNIDILFRL AKEEISKSPE HTDRFSRLVR
     HVLQQHTYYP MFPHALGDSI DASQLVNIQV SWLPDILILP SQFKYFVKNV DDVVCINPGH
     LCKSLAAGSY ARVVLYPTTD VNNQVRVDLF KL
//