ID   A0A0C9MTH6_SPHPI        Unreviewed;       297 AA.
AC   A0A0C9MTH6;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE            EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN   ORFNames=SP6_30_01720 {ECO:0000313|EMBL:GAN14031.1};
OS   Sphingomonas paucimobilis NBRC 13935.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1219050 {ECO:0000313|EMBL:GAN14031.1, ECO:0000313|Proteomes:UP000032025};
RN   [1] {ECO:0000313|EMBL:GAN14031.1, ECO:0000313|Proteomes:UP000032025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 13935 {ECO:0000313|EMBL:GAN14031.1,
RC   ECO:0000313|Proteomes:UP000032025};
RA   Hosoyama A., Hashimoto M., Hosoyama Y., Noguchi M., Uohara A., Ohji S.,
RA   Katano-Makiyama Y., Ichikawa N., Kimura A., Yamazoe A., Fujita N.;
RT   "Whole genome shotgun sequence of Sphingomonas paucimobilis NBRC 13935.";
RL   Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC         Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC         ChEBI:CHEBI:140347; EC=3.5.2.6;
CC         Evidence={ECO:0000256|ARBA:ARBA00001526};
CC   -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC       {ECO:0000256|ARBA:ARBA00009009}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAN14031.1}.
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DR   EMBL; BBJS01000030; GAN14031.1; -; Genomic_DNA.
DR   RefSeq; WP_007404909.1; NZ_BBJS01000030.1.
DR   AlphaFoldDB; A0A0C9MTH6; -.
DR   Proteomes; UP000032025; Unassembled WGS sequence.
DR   GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR045155; Beta-lactam_cat.
DR   InterPro; IPR000871; Beta-lactam_class-A.
DR   PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR   PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13354; Beta-lactamase2; 1.
DR   PRINTS; PR00118; BLACTAMASEA.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251}.
FT   DOMAIN          46..262
FT                   /note="Beta-lactamase class A catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF13354"
SQ   SEQUENCE   297 AA;  32002 MW;  83F60C562A9A8D3C CRC64;
     MNRRDLMLSI GASLALGGRA DAGTSMRDPT ARLRAIERAS GGRLGAFVLD TGSGRSFGWR
     ADERFCHCST FKLSLAAMAL READAGRLDL METLAFSRAD IVAYSPIVEE NLDKGKLPIL
     ALAQAVQITS DNAAANVLMH RLGGPAALTR FWREIGDAVS RLDGYEPAIN VIPPGTQENS
     TTPRAMAETV RRIVLGDVLR PASRDRLRSW MAATQSGSKR IRAGLPADWH GFDKTGTGMR
     PGIGNKTNDL AVLMPPKGRS PLVVTGYFEN PSFSEDVRPA DEAVLKMLGR LAVAWNG
//