ID A0A0C9MVC4_9FUNG Unreviewed; 584 AA.
AC A0A0C9MVC4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 08-NOV-2023, entry version 27.
DE SubName: Full=Carotenoid cleavage dioxygenase 1 {ECO:0000313|EMBL:GAN07437.1};
GN ORFNames=MAM1_0161c06934 {ECO:0000313|EMBL:GAN07437.1};
OS Mucor ambiguus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN07437.1};
RN [1] {ECO:0000313|EMBL:GAN07437.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN07437.1};
RA Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT ambiguus NBRC6742.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; DF836450; GAN07437.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9MVC4; -.
DR STRING; 91626.A0A0C9MVC4; -.
DR OrthoDB; 294919at2759; -.
DR Proteomes; UP000053815; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000313|EMBL:GAN07437.1};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Oxidoreductase {ECO:0000313|EMBL:GAN07437.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053815}.
FT BINDING 238
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 293
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 366
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 570
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 584 AA; 65845 MW; 8B3374402A9C8107 CRC64;
MIVELLTLIS LSVSGFVLFL YRNYYNDVYK RFQVILKSHK LSNTPEVQDP IVLQVQSGQI
PSWLNGIMYR IGPGRFNIQQ DDGSTFSIRH AFDGLPFMHR FEVNGSTQTL KYNSRMLAKS
LETKIKSKTS KGLIFFGHIP EMTFPEWLYN FYVRFNNLIL FPKARDNAGP DGQAVGVTVT
PNFPLPAKIR KTDNENVLVS KTDANVLQKI HAETLEPQNI FTYTSYDARV KGQLSAAHHQ
YDHNTKEIFN FALTTGPVPR LVVFSTSEAG KVTILADFTH RTDKSSIQAP YIHSLWLTEN
YVIIPESPMV LKDRGANMLM NGSFLSSISW VKDAPTYCHV ISRHPAQEKE GLVASIPVNP
GFFTFHVGNA FETKNESGET ILTLDAASFW DGDIMHQLHG FGTPHRKGFV AEKVKQSTLN
GISYPPRQQS GFGDLVRYKL NLDQSTTLSI DTLAKNVEFP RFNQDYALKE ESRFVYGCQL
QGFTEKRDET GGLIKVDLTG QTEPLTFVEE GFNCSEPIFV PNPTGTKEDD GVLLSLVNNF
DCCYFIVFDA SNLEELARIK IGQFIAVTFH GSYVDHEFKS ININ
//
