ID A0A0C9MXQ4_9FUNG Unreviewed; 1199 AA.
AC A0A0C9MXQ4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Heavy metal translocating P-type ATPase {ECO:0000313|EMBL:GAN06983.1};
GN ORFNames=MAM1_0143c06473 {ECO:0000313|EMBL:GAN06983.1};
OS Mucor ambiguus.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Mucorineae; Mucoraceae; Mucor.
OX NCBI_TaxID=91626 {ECO:0000313|EMBL:GAN06983.1};
RN [1] {ECO:0000313|EMBL:GAN06983.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NBRC 6742 {ECO:0000313|EMBL:GAN06983.1};
RA Takeda I., Yamane N., Morita T., Tamano K., Machida M., Baker S., Koike H.;
RT "Draft genome sequence of an oleaginous Mucoromycotina fungus Mucor
RT ambiguus NBRC6742.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362081}.
CC -!- SIMILARITY: Belongs to the cation transport ATPase (P-type) (TC 3.A.3)
CC family. Type IB subfamily. {ECO:0000256|RuleBase:RU362081}.
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DR EMBL; DF836432; GAN06983.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9MXQ4; -.
DR STRING; 91626.A0A0C9MXQ4; -.
DR OrthoDB; 5480493at2759; -.
DR Proteomes; UP000053815; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0019829; F:ATPase-coupled monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR CDD; cd00371; HMA; 4.
DR CDD; cd02094; P-type_ATPase_Cu-like; 1.
DR Gene3D; 3.30.70.100; -; 4.
DR Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR InterPro; IPR018303; ATPase_P-typ_P_site.
DR InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR InterPro; IPR036412; HAD-like_sf.
DR InterPro; IPR023214; HAD_sf.
DR InterPro; IPR017969; Heavy-metal-associated_CS.
DR InterPro; IPR006122; HMA_Cu_ion-bd.
DR InterPro; IPR006121; HMA_dom.
DR InterPro; IPR036163; HMA_dom_sf.
DR InterPro; IPR027256; P-typ_ATPase_IB.
DR InterPro; IPR044492; P_typ_ATPase_HD_dom.
DR NCBIfam; TIGR01525; ATPase-IB_hvy; 1.
DR NCBIfam; TIGR00003; copper ion binding protein; 4.
DR PANTHER; PTHR43520; ATP7, ISOFORM B; 1.
DR PANTHER; PTHR43520:SF8; COPPER-TRANSPORTING ATPASE 2; 1.
DR Pfam; PF00122; E1-E2_ATPase; 1.
DR Pfam; PF00403; HMA; 4.
DR Pfam; PF00702; Hydrolase; 1.
DR PRINTS; PR00119; CATATPASE.
DR PRINTS; PR00942; CUATPASEI.
DR SFLD; SFLDS00003; Haloacid_Dehalogenase; 1.
DR SFLD; SFLDF00027; p-type_atpase; 1.
DR SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR SUPFAM; SSF56784; HAD-like; 1.
DR SUPFAM; SSF55008; HMA, heavy metal-associated domain; 4.
DR PROSITE; PS00154; ATPASE_E1_E2; 1.
DR PROSITE; PS01047; HMA_1; 4.
DR PROSITE; PS50846; HMA_2; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU362081};
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362081};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU362081};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU362081};
KW Reference proteome {ECO:0000313|Proteomes:UP000053815};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362081};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362081}.
FT TRANSMEM 352..373
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 385..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 428..450
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 456..477
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 617..639
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 664..687
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 1048..1071
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT TRANSMEM 1077..1096
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362081"
FT DOMAIN 6..72
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 74..140
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 187..253
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
FT DOMAIN 261..327
FT /note="HMA"
FT /evidence="ECO:0000259|PROSITE:PS50846"
SQ SEQUENCE 1199 AA; 128410 MW; 3D54557E1514EC08 CRC64;
MSRLVHTTRL PVQGMTCQSC VRAITNAVSE MDGVDAVQVD LEAAAATITH DALLLTFTDL
KNCIEDCGFD VDITTITLPV LGMTCQSCVK AITTVLSDKQ GIISAQVDLQ QEEATVTYDP
KLIGTPEIVD LIEDCGFDVI MSNTDASQHT QIKTPPSTAY KTQATTTKEK LQHDQMATTT
TTTTSANSVQ LEIRGMTCAS CVTSIEKALK SHKGISYVSV ALLAERATVD YDPLYILPDT
IADIINDAGF EANVIQRKQD DLLQLQIYGM TCASCVAGIE GGLRALPGVM EVSVNLMTET
AKVKFNCHIT NPRAIVEEIE SLGFNAILAN ATKDAQLESL SKIREIKEWK MAFTECLFFA
VPVFFIAMVL PMFSWSPVIT EIPFFVPGVF LVDATQLLLT IPVQFGVGKR FLRSAYVSVL
HGAPTMDVLV SISTLAAFGF SVLSMLNAFF TQAKVAPTVF FDTSTMLITF IVLSRYLENK
AKGESSSALS KLMSLAPSTA LMVTVDEHHV VLTERKIPSE LISEGDLLKL VPGDKVPADG
EIFSGSSTID ESMVTGEVDA VPKNVGDTVI GGTVNGLGTF IMKATRVGAD TALSQIVKLV
EDAQVSKAPI QGFADTVAGY FVPTVVMLGL GTLIVWSVLV KSLGVDHLPV ILQKEILNNG
DGGWFFVCLK LCISVIIVAC PCALGLATPT AVMVGTGVGA ENGVLFKGGA VLENGQAVNK
VVFDKTGTLT CGKLDLVESK SWNGAEEHRV QMLILSAIAE SHSEHLLGRA VVATGRELTG
LAVLDSLATV DNFISVTGFG ISCDITLNHA LPLDVNPAVA SCLAPLLNTS HTLVIGNKKW
LEEHNGIGLS DEQEAAYQAQ GSLGRTCVLV GIDGLPAGFI SLSDVVKPEA KQVIATLHAM
GIQTAMITGD NELTARCIAA QLGITEVHAG VSPNGKTQII KRMQEQTFAR KQVPWWSRLR
NSNSSSNQYL PLYENNSCTG NKTVVAMVGD GINDSPALVA SNLGIALCSG TDIAMEAADV
ILMRNDLTDV VAALDLSKAI FHKIRMNLLW ACIYNLIGIP LAMGIFLPWG YRLHPMMAGI
AMGASSTSVV LSSLALRWSW KRPILESLDD FEHGSSNDAA VRLSLLVHEM RDEQDIEMTL
HQVGSSSPTA SISDTEHDGL LNATKRHTKV SVVNRLKSVF SKKSSTSEYT AVSAQDDDF
//
