ID A0A0C9TFZ4_PAXIN Unreviewed; 913 AA.
AC A0A0C9TFZ4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Protein HIR {ECO:0000256|RuleBase:RU364014};
GN ORFNames=PAXINDRAFT_169722 {ECO:0000313|EMBL:KIJ14575.1};
OS Paxillus involutus ATCC 200175.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Paxilineae; Paxillaceae; Paxillus.
OX NCBI_TaxID=664439 {ECO:0000313|EMBL:KIJ14575.1, ECO:0000313|Proteomes:UP000053647};
RN [1] {ECO:0000313|EMBL:KIJ14575.1, ECO:0000313|Proteomes:UP000053647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200175 {ECO:0000313|EMBL:KIJ14575.1,
RC ECO:0000313|Proteomes:UP000053647};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 200175 {ECO:0000313|Proteomes:UP000053647};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for replication-independent chromatin assembly and
CC for the periodic repression of histone gene transcription during the
CC cell cycle. {ECO:0000256|RuleBase:RU364014}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU364014}.
CC -!- SIMILARITY: Belongs to the WD repeat HIR1 family.
CC {ECO:0000256|ARBA:ARBA00007306, ECO:0000256|RuleBase:RU364014}.
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DR EMBL; KN819342; KIJ14575.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9TFZ4; -.
DR HOGENOM; CLU_004372_3_0_1; -.
DR OrthoDB; 5478541at2759; -.
DR Proteomes; UP000053647; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006338; P:chromatin remodeling; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR031120; HIR1-like.
DR InterPro; IPR011494; HIRA-like_C.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13831; MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS; 1.
DR PANTHER; PTHR13831:SF0; PROTEIN HIRA; 1.
DR Pfam; PF07569; Hira; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853,
KW ECO:0000256|RuleBase:RU364014}; Nucleus {ECO:0000256|RuleBase:RU364014};
KW Reference proteome {ECO:0000313|Proteomes:UP000053647};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364014};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|RuleBase:RU364014};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU364014};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU364014};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 23..48
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 70..104
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 128..159
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 170..201
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 663..854
FT /note="Protein HIRA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07569"
FT REGION 388..432
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 416..432
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 913 AA; 99726 MW; 83F501BB01AF904A CRC64;
MRFTKPSWVM HKDSAKDTKR LSIFSVHVHP DGSRIATGGL DAKVRIWSTK PILNSASERS
NRPPKSLCTL SMHTGPVLTV RWAHSGRWLA SGSDDEIVMI WDLDPSGRGK VFGSNEINIE
NWKPLKRLPG HESDVTDIAW APEDRYLASV GLDSNVIVWC GYTLERIRKL DQHNGFVKGV
CFDPVGEFMA TQSDDKSVKI WRTTDWGLEA EIRKPFEDSP GSTFFRRLSW SPDGAHITAS
NATNNRGFVF IAAVITRGLW TSEISLVGHE NTVEVASYNP HIFLRNPSAP IATSNICSVV
ALGADDRSVS IWQTKSARPL IVAREVFERQ IMDLSWSRDG LTLYAASSDG TVAVFDFDAE
ELEGIAPYGA QAQYLQKFGF VPPPVPEGFS HGTSCEGEHA PSASRITPPP SPTPRASTQA
SQSGFGTSAV NGGEQINRLV AKKSKKKHVQ PVLMSSIPSA STTLSKVAPS VSGRGPVNGN
ALGISTSERR PLAARAAPVS RSVSPAPSMR GFDADIEMGG SMDMEVPIDS LDQGSSPEMP
KGKRKASVME LDDRPVRPRT LGGDRNRESV AVREIARVGE TWDALPALRS AEVLPSPPVL
TFEDVLEGRN SEGDGPTEVL FVSSKQTQWL DYLPSPVVAL TASPSFCAVA TQDGSVNIYS
HTGRRIMSTL SLGSPCAMIH SCKSALLLLS TLGRLSCINV KSQSAYFPPV SVDSLISTPN
CTILSATIRP NGAPVIQCSS GITYSYDPQL SSWIKLSERW WAEGSDVWQG RQRSNREVVA
SIEGAISTTA GTSEHRERPE WWNTALTLGH LESKMHASKA LDSPTEYKQA LLLYAKKIAD
EGFRAKAEEL IRDLFGPVFW RPGRDDWCPT IVGMLKRDLL REVLSVFARS KTLTKLALDW
QDTLKKATND EST
//
