ID A0A0C9Y821_9AGAR Unreviewed; 943 AA.
AC A0A0C9Y821;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=TFIIS N-terminal domain-containing protein {ECO:0000259|PROSITE:PS51319};
GN ORFNames=K443DRAFT_81434 {ECO:0000313|EMBL:KIK10184.1};
OS Laccaria amethystina LaAM-08-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=1095629 {ECO:0000313|EMBL:KIK10184.1, ECO:0000313|Proteomes:UP000054477};
RN [1] {ECO:0000313|EMBL:KIK10184.1, ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|EMBL:KIK10184.1,
RC ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcription factor involved in RNA polymerase II
CC transcription regulation. May function in both SPT15/TBP post-
CC recruitment and recruitment steps of transcription.
CC {ECO:0000256|ARBA:ARBA00037349}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00649}.
CC -!- SIMILARITY: Belongs to the IWS1 family.
CC {ECO:0000256|ARBA:ARBA00037992}.
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DR EMBL; KN838536; KIK10184.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9Y821; -.
DR STRING; 1095629.A0A0C9Y821; -.
DR HOGENOM; CLU_326233_0_0_1; -.
DR OrthoDB; 12240at2759; -.
DR Proteomes; UP000054477; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR InterPro; IPR017923; TFIIS_N.
DR PANTHER; PTHR46010; PROTEIN IWS1 HOMOLOG; 1.
DR PANTHER; PTHR46010:SF1; PROTEIN IWS1 HOMOLOG; 1.
DR Pfam; PF08711; Med26; 1.
DR PROSITE; PS51319; TFIIS_N; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00649}; Reference proteome {ECO:0000313|Proteomes:UP000054477}.
FT DOMAIN 188..266
FT /note="TFIIS N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51319"
FT REGION 1..124
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 527..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..664
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 706..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..96
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..124
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 398..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..664
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 710..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..775
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 849..881
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KIK10184.1"
SQ SEQUENCE 943 AA; 104483 MW; 6CEA6DC051442BE9 CRC64;
DRNKLEREVF GGSESELSSD EDEELQPQLQ QKEQPRPVKP PVDDYESSGG DSEDDYEQQR
PVKPTKKKRL SKKGPEDVER RPVQRKRKRK QPVEVDLSEL PPEQEAILKP KKASRQRKKK
ANEEVLDSFA DDEVARLREV MNTAADEDIR ANNEKQPATA KLKLLPEAME TLRKAALAQS
MIDNNLLEAV RRWLEPLPDR SLPALNIQRE LFNIIRKMEF IDSAVLKESG LGRVVLFYTK
CKRVTGDIGR IANELVSTWS RPIIKRSASY RDRVVPVAQE GGDVDMRAGE RLNAILARAK
EGEKGRVKQN AVLIPQRELG SYTVAPKVNG GIGRVNLSVD VDIERRRKNA ERLRSLTRKP
NFLLSLSINL IHMQTRRSTR VSPLAIVLPH PPLPHRRSSR LSANSTPQTP RSCASPSIFF
TSSNRKSTDS WNSSNADDME YDWKSEQVLL LSRTLDALPA HLVTPFNGPI PPSNLLDKIA
RGVSQAKGPA DWPHSLRATR VKIIELCRAK AREEEQQRKV IEEEVEVDDH PYYHDGEEKP
LRDGPTGIQS RRPLYRQSSM DFIQVDAKEN DNITRLSNRL QRTDRINPAY HPYSCTRSAL
HRRDSSPPLL SDLPSLINPS TPSSSTLTSL SSLSSRPRAL RRTSSTLSSA SISMLSNSSK
GVSLADPRVQ RVLRSDSFCG LAPAPPPKDI LPTSIGFKRA PSFGTLAQEA KREAESRRHV
RQDSGSYLSS DEEERIRTRQ AKKPRTKAGS PASNDSPVMA TPPASSPSGT SSAPSPLMDK
APLPPAKDKT PFKSRSKSKG MVACLEGTPK SPKPKSAGKK DKAARPMPMN LQRNPSMFGA
ELPHLCSPSN TPAIASPSPT RENASKAQVS SPVTAILTRS PSIPPSPSPP STQKVKTLRR
VRRLAPARRI SFGSLVAPGD EADGEGEGEH EEKLALGSAF QLH
//
