ID A0A0C9Y8L4_9AGAR Unreviewed; 1000 AA.
AC A0A0C9Y8L4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Rho1 guanine nucleotide exchange factor 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=K443DRAFT_670999 {ECO:0000313|EMBL:KIK10379.1};
OS Laccaria amethystina LaAM-08-1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Hydnangiaceae; Laccaria.
OX NCBI_TaxID=1095629 {ECO:0000313|EMBL:KIK10379.1, ECO:0000313|Proteomes:UP000054477};
RN [1] {ECO:0000313|EMBL:KIK10379.1, ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|EMBL:KIK10379.1,
RC ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LaAM-08-1 {ECO:0000313|Proteomes:UP000054477};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN838536; KIK10379.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9Y8L4; -.
DR STRING; 1095629.A0A0C9Y8L4; -.
DR HOGENOM; CLU_005275_0_0_1; -.
DR OrthoDB; 5100844at2759; -.
DR Proteomes; UP000054477; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054477}.
FT DOMAIN 235..430
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 465..596
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 632..949
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 74..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1000 AA; 111846 MW; 51876A58F6132E13 CRC64;
MQHNVDGADG HHRPHVSLAV GGHLPFGSRN PMHPSPARFP AYTFDLSPPA YDGDLPNPLD
TQHASSTLLE NARPPMANER HHRPSSRSTS FSVIGTPSIA FPEPQIYRSV SHKQSSREST
LQPPSTSRPP NHHFTQSDLG PTRSIGMHQD PSVASFRSTA SSYYQNNDDY NYTSPTNEFF
ADDTDDITRE LSDFTLNSEE GLRRFQNGEL AEADQEWHRL VPNEARDALG KKEVQRQSVL
FEIFKAEREY VADLEAVEEV FIAGLMKASP PIIPESQLSG FIHEVFGNLN QILTYHQAML
AALFARQRDQ HPLIQSVADI VLDTTLKSDF RSAYETYIKH YPLSESHHRK QLKKNHAYAA
FIQSVSTDQR IRKRDLITFL SRPVTRLPRL NLLLEQTLKL TDEMHDHPDL ETLPIILGIL
KDCIKSTQPG IEAAESKVKF WELCESLVYQ KGEIIDMDLY DESRTFVYSG PVSRRARSET
GFSSGGWTEL VAALLDNFFV LTREEKRPSG SVKRLIMSRP IPLSFLRLGT FDSAPETRRE
RAEDGGLLDS LRYQTVTLYP FTVYHASNRS TRRYTLYVTT EALRKRWQSV LVETIGVFKV
RQDSNMWFDP QKVSDNFFRV PGRRSEPAVR TSGRINSGVP FNYGGRKFIV VGCASGIYLA
HHGTEQFRKV LNNVNPASIS ALQTLGNKMF NKLVVHADAS VYSYSLETIV RVGLGHAHPQ
TIEVVAERIG GSDNNILFCK HLQIGARLLL VYASKKRLST TLNLHVLEAI DTSKVMPSPT
RTAATSIVSY RPYGDPGYVP KDAYDVVGLV KTIGICTNDG IVTVDPTNLA LSDVAVVPDL
QGASNNPPVA ALKVNLEGAK PLGLLRVDAN ELLVVYDVLG CYINRRGQPT RQSGYIKWET
KATSYAHRQG HVLLFSPEFI EIRSAINGRI VQVIEGNDIR LLFSGPMTSK DDPVMFAMRG
DKDDGGGVSE KIVELKETSE IAPVTPLSAS VPVMWDEWDM
//
