ID A0A0C9Z1Z7_9AGAM Unreviewed; 779 AA.
AC A0A0C9Z1Z7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Unplaced genomic scaffold scaffold_47, whole genome shotgun sequence {ECO:0000313|EMBL:KIK23031.1};
GN ORFNames=PISMIDRAFT_11168 {ECO:0000313|EMBL:KIK23031.1};
OS Pisolithus microcarpus 441.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Sclerodermatineae; Pisolithaceae; Pisolithus.
OX NCBI_TaxID=765257 {ECO:0000313|EMBL:KIK23031.1, ECO:0000313|Proteomes:UP000054018};
RN [1] {ECO:0000313|EMBL:KIK23031.1, ECO:0000313|Proteomes:UP000054018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=441 {ECO:0000313|EMBL:KIK23031.1,
RC ECO:0000313|Proteomes:UP000054018};
RG DOE Joint Genome Institute;
RA Kuo A., Kohler A., Costa M.D., Nagy L.G., Floudas D., Copeland A.,
RA Barry K.W., Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A.,
RA Lipzen A., Lundell T., Morin E., Murat C., Sun H., Tunlid A., Henrissat B.,
RA Grigoriev I.V., Hibbett D.S., Martin F., Nordberg H.P., Cantor M.N.,
RA Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054018}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=441 {ECO:0000313|Proteomes:UP000054018};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in cytoskeletal rearrangements required for
CC phagocytosis of apoptotic cells and cell motility. Acts in association
CC with DOCK1 and CRK. Was initially proposed to be required in complex
CC with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine
CC nucleotide exchange factor (GEF) activity of DOCK1.
CC {ECO:0000256|ARBA:ARBA00024863}.
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DR EMBL; KN833731; KIK23031.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0C9Z1Z7; -.
DR STRING; 765257.A0A0C9Z1Z7; -.
DR HOGENOM; CLU_009191_1_0_1; -.
DR OrthoDB; 1473500at2759; -.
DR Proteomes; UP000054018; Unassembled WGS sequence.
DR GO; GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024574; ELMO_ARM.
DR InterPro; IPR006816; ELMO_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR12771:SF56; CED-12; 1.
DR PANTHER; PTHR12771; ENGULFMENT AND CELL MOTILITY; 1.
DR Pfam; PF11841; ELMO_ARM; 1.
DR Pfam; PF04727; ELMO_CED12; 1.
DR Pfam; PF16457; PH_12; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51335; ELMO; 1.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Phagocytosis {ECO:0000256|ARBA:ARBA00022907};
KW Reference proteome {ECO:0000313|Proteomes:UP000054018};
KW SH3-binding {ECO:0000256|ARBA:ARBA00023036}.
FT DOMAIN 372..527
FT /note="ELMO"
FT /evidence="ECO:0000259|PROSITE:PS51335"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 779 AA; 87575 MW; 33960FFB736C93CB CRC64;
MSSANTSTRA TPSPLTTNGI TPKSTAGIIP TNNVTTKSGV TVRARIDPTL TVEDVVRQLC
LHLKVAEPHT NLALRDRDTE ELITSENLRK KIKNKVHLKL VNSSAIEAAG IIEKLGRRDE
KSLRMSLFSL QKFIKEEKFA QEFLDRDGLR ELVDVIDTTH GNTLAYALTA MQNLMDLDYG
WSTLDDSFIF KVVQILSSPN SLINVCRPAT AILKKLVEAD PANVVNPIVA SSSRAPPVAP
PGSVYRYGFQ SVYEQMHRQK GSLETVVSRL GSPDTAMAQH RQVHWILLLH STRTTAFHSM
MLINSLLSNV NDTYWDEFIA DLERLNIRKA AIRLMSSHVD DLTSCVLDFQ ANIVRVTYKK
KITVVEPEVE LAHLSGLHYI WECSGVQEEV DSEGQPLKWR KLGFDSENIM EEFQDAGVLG
LDCLVNFVQD DPDFFSKVIL EQLSRPEERR CPVAKASNEI VELLSQHWTI YAPAYSTSTF
QPFFLNFPKV HCLALHFFLR MWNESGSAAD DFSRISALTR SQIKVALQQE SVRPWHEVEH
DFLECEYRAV RDRQMQELEA GDDLLSRVPV RNLKEKLTRE SAEFVRQQRI HCLLQGAWFL
NGVPTQHTGS ARRPNGQWRF MRLDNGLKYL HYVDSPVKFD VRNGTEDLPE RIEIASISQI
TTGTCAPPPN LARDHPDLPT SLLPSPLSFS LLSGGGESLA DQIATDQSRW ADWTDGLNML
RRDSGHVTSE ETAGYIKALT EIGLKIKLLD LSGEKVDIPS GLVTGPPPTN TEFFFSDLQ
//
