ID A0A0D0AW09_9AGAM Unreviewed; 747 AA.
AC A0A0D0AW09;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Apyrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CY34DRAFT_809240 {ECO:0000313|EMBL:KIK38562.1};
OS Suillus luteus UH-Slu-Lm8-n1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Boletales; Suillineae; Suillaceae; Suillus.
OX NCBI_TaxID=930992 {ECO:0000313|EMBL:KIK38562.1, ECO:0000313|Proteomes:UP000054485};
RN [1] {ECO:0000313|EMBL:KIK38562.1, ECO:0000313|Proteomes:UP000054485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UH-Slu-Lm8-n1 {ECO:0000313|EMBL:KIK38562.1,
RC ECO:0000313|Proteomes:UP000054485};
RG DOE Joint Genome Institute;
RA Kuo A., Ruytinx J., Rineau F., Colpaert J., Kohler A., Nagy L.G.,
RA Floudas D., Copeland A., Barry K.W., Cichocki N., Veneault-Fourrey C.,
RA LaButti K., Lindquist E.A., Lipzen A., Lundell T., Morin E., Murat C.,
RA Sun H., Tunlid A., Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.,
RA Nordberg H.P., Cantor M.N., Hua S.X.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UH-Slu-Lm8-n1 {ECO:0000313|Proteomes:UP000054485};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
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DR EMBL; KN835386; KIK38562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D0AW09; -.
DR STRING; 930992.A0A0D0AW09; -.
DR HOGENOM; CLU_010246_3_1_1; -.
DR InParanoid; A0A0D0AW09; -.
DR OrthoDB; 180318at2759; -.
DR Proteomes; UP000054485; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IEA:UniProt.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
DR PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Hydrolase {ECO:0000256|RuleBase:RU003833};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000054485};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 557..579
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 499..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 637..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 164
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 195..199
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 747 AA; 81726 MW; A343F8B36B4D55BF CRC64;
MPPTTSSNSW LTARRFGIVI DAGSSGSRLQ IYSWEDPDVV LSEQGDDVWD KLPKVEKGVQ
EGDDWIMKAE PGLSTFADNS EGVHEYLAPL LKHARSQIPP SLESETPLFL LATAGMRLLT
PVQQARVLSA TCKYLKSASS FRIDDESKDG PCGSSVRIIT GEEEGLYGWI AVNYLMDGFY
GKDKKTTYGF LDMGGASTQI AFEPSDTLSG DKENLVDVRL RLLGGDEVNH SVFVTTWLGY
GTNQARERYV AKTVEHFKET LLETSESSFI PDPCLPKDLI LSETLPQIDG SHSIHRLTGT
GSFTQCLDRT ASLLNKNAPC NTAPCLFDGV HVPAINFASS HFIGVSEYWY SSEHVFGLGG
PYDYVQYERA ATQFCGRDWS GIVSQHELST AQGIRGGDGE VMENGEIMEV GKWGKNVELP
RLQMQCFKAA WIANVLHEGI GIPRIVDPEG NSTTVGEQVA HQAEVKGLGR PVFQSVDSIG
DIAISWTLGK MVLEASKEIK PSSSSSRPLA DPIDDIPAST PNPPIKPIRP FWDLDQLLEE
HVSPHLPASL TRESLGFSPI TILSYAIILI VVSCIVFRLR HPLRVARRRL LRGSFKRDLH
GAYAMEEGIA TPRPPSPSNS SFLPPSLLRP LRRLVSSSTS SSRPRLTPIS TSLHPPSIRH
TQASVLSPPP YHNASDGFST STSTSHPHSR ASSPIAATAP DDTIMTSSRS SISSINPRSR
NSSHMNLTLF PRQTLSRANS ILQLPDE
//
