ID A0A0D0CPB0_9AGAR Unreviewed; 1172 AA.
AC A0A0D0CPB0;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=GYMLUDRAFT_247376 {ECO:0000313|EMBL:KIK57123.1};
OS Collybiopsis luxurians FD-317 M1.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Omphalotaceae; Collybiopsis;
OC Collybiopsis luxurians.
OX NCBI_TaxID=944289 {ECO:0000313|EMBL:KIK57123.1, ECO:0000313|Proteomes:UP000053593};
RN [1] {ECO:0000313|EMBL:KIK57123.1, ECO:0000313|Proteomes:UP000053593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FD-317 M1 {ECO:0000313|EMBL:KIK57123.1,
RC ECO:0000313|Proteomes:UP000053593};
RG DOE Joint Genome Institute;
RG Mycorrhizal Genomics Consortium;
RA Kohler A., Kuo A., Nagy L.G., Floudas D., Copeland A., Barry K.W.,
RA Cichocki N., Veneault-Fourrey C., LaButti K., Lindquist E.A., Lipzen A.,
RA Lundell T., Morin E., Murat C., Riley R., Ohm R., Sun H., Tunlid A.,
RA Henrissat B., Grigoriev I.V., Hibbett D.S., Martin F.;
RT "Evolutionary Origins and Diversification of the Mycorrhizal Mutualists.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN834793; KIK57123.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D0CPB0; -.
DR HOGENOM; CLU_001251_1_0_1; -.
DR OrthoDB; 2044425at2759; -.
DR Proteomes; UP000053593; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 2.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR041675; PH_5.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR46572; RHO1 GDP-GTP EXCHANGE PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR46572:SF1; RHO1 GUANINE NUCLEOTIDE EXCHANGE FACTOR TUS1; 1.
DR Pfam; PF00780; CNH; 2.
DR Pfam; PF15405; PH_5; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 2.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053593}.
FT DOMAIN 502..717
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 733..859
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 62..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 401..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 671..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..689
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1172 AA; 131962 MW; 5580A565F0AD5872 CRC64;
MPHNQPSSPV LGDQDLQQIY EQVSAGFDSE EDDTLTTNIE SSSITSRNST FSADFSFFTA
ESQPRTGNNY EKLSEAPADK DKEGDATIHS TYAAHPFRES TSSYQHRHRN SDFSYDDFLI
SPESPVSTAA AKKPWKDTVP EGVLSRIGEE EVNRQVEIHD LVAKETEYLE QLIILETDFL
RPLTEWVKKK EDEREREQAD VGRITSASNY LPLLRFSPAL HFLLRILNFL IASHTRLLED
LHARESQHGI IEQIGDLYLE RAAGEWKAGW GNGWVEGKGF VSGGGEWTGD SGYDEWVAVW
TTSGLGGLNI FSDNNKSGMW GSEEWKAVVA EQMRVHQMTG AIVDERGRTR YTTFLTTDSV
PDIDLKRFSE LLVLPVTHFQ LYPSFFSTIL SSYYDVTSAP AAASSPSGSS TDPAARKDSK
HQGGKEKGRE ENPDESYLRE AIRAMRALWG YAKVKTFQMS MNIEASENNG GKGSMGDAAV
KWEWFDLTSE EERKEIGKAE MKRQAIIFEL IKGEMRYVRD LENVEHIYIA PLQNASTSVN
PITPAERLPQ FIQSVFSNIN ALHSHHLRLL QSLFRIQYDE KPTIRSISAP ILDAALNWRE
AYTEYIPNYP IATYTIDSEM RINQAFREFV QRCTRHPDAH RLDMKNFINR PIPRLLRHEL
LLKGILEETP SGPLGVPGSS RQGASSSRGL NGEHEDHTAI PQVLDVIRRL GKDTEPGVQG
EWIDMDWLDE HRSLIYSGKL LRQTDGLERD RWTELYVLSF VVMIKVKEHD EGRKYRVDRR
PIPLDLLTID SLTDAPVQRS PYPSRLTIDS LTDVPVQRNT DRSIFQFPFE GRIGLSPNLY
AESERVRTEW RAKLQEASTH RATQGNNKVF EVKLLGGDTF LTRDGEDGSS NGSYGDVLDS
TYCRSFTGKI PQIEENWSLL SVRKVSGLGS GMSLTLVSQC AVLGDYGLFL VLADKQLFAY
LIDALVPSSP LTANVSQVVQ KLSGSDDVHF FTVGILLGRT LVIYMRKRGL DSIFRVLEPV
SEKIHEQVNA PSRFGSISFP RSPNRSTLFP HARISSYPLN QFGVYVDQHG NPSRAVRIIE
WEGDAERIAV HAQSILRFDS RFIEIRSLET GRLAQIIPGS DIRCIWDGRG VSSLNAIQNA
QVHAVMNTPE TVIGLGPRAI IQQVIEILPT VS
//
