ID   A0A0D0EFQ1_9FLAO        Unreviewed;       931 AA.
AC   A0A0D0EFQ1;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Peptidase M16 {ECO:0000313|EMBL:KIO54494.1};
GN   ORFNames=IW18_00270 {ECO:0000313|EMBL:KIO54494.1};
OS   Flavobacterium hibernum.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=37752 {ECO:0000313|EMBL:KIO54494.1, ECO:0000313|Proteomes:UP000032061};
RN   [1] {ECO:0000313|EMBL:KIO54494.1, ECO:0000313|Proteomes:UP000032061}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12611 {ECO:0000313|EMBL:KIO54494.1,
RC   ECO:0000313|Proteomes:UP000032061};
RA   Stropko S.J., Pipes S.E., Newman J.D.;
RT   "Genome of Flavobacterium hibernum DSM 12611.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M16 family.
CC       {ECO:0000256|ARBA:ARBA00007261, ECO:0000256|RuleBase:RU004447}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KIO54494.1}.
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DR   EMBL; JPRK01000002; KIO54494.1; -; Genomic_DNA.
DR   RefSeq; WP_041515587.1; NZ_UGGR01000002.1.
DR   AlphaFoldDB; A0A0D0EFQ1; -.
DR   STRING; 37752.IW18_00270; -.
DR   OrthoDB; 9811314at2; -.
DR   Proteomes; UP000032061; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.30.830.10; Metalloenzyme, LuxS/M16 peptidase-like; 4.
DR   InterPro; IPR011249; Metalloenz_LuxS/M16.
DR   InterPro; IPR011765; Pept_M16_N.
DR   InterPro; IPR001431; Pept_M16_Zn_BS.
DR   InterPro; IPR007863; Peptidase_M16_C.
DR   PANTHER; PTHR11851; METALLOPROTEASE; 1.
DR   PANTHER; PTHR11851:SF229; PEPTIDASE M16 DOMAIN PROTEIN; 1.
DR   Pfam; PF00675; Peptidase_M16; 2.
DR   Pfam; PF05193; Peptidase_M16_C; 2.
DR   SUPFAM; SSF63411; LuxS/MPP-like metallohydrolase; 4.
DR   PROSITE; PS00143; INSULINASE; 1.
PE   3: Inferred from homology;
FT   DOMAIN          48..195
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          207..380
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
FT   DOMAIN          523..641
FT                   /note="Peptidase M16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00675"
FT   DOMAIN          678..856
FT                   /note="Peptidase M16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05193"
SQ   SEQUENCE   931 AA;  103006 MW;  8C3B07EB5558C69B CRC64;
     MKKHIFLGYC SLAFCTLISA QNKSAKFNKI KELGGIEEYL YQPNGMNVLL LQDNASPVVT
     VQIVYRVGSK NEVLGNTGST HLLEHLMFKG TPTFNKKTGT TITDVLQNTG AQLNATTWYD
     RTNYFETLPS DKIALALQIE ADRMRNSLLL KEDKEAEMTV VRNEFERGEN NPNSLLDKEI
     WAAAYIAHPY HHSTIGWKSD IEKAPIEVLR NFYNTYYWPD NATLTIIGDF KKENVFELIE
     QYFGKITKAP NAMPQPYTEE PQQYGPRKIV VRKPGELGVV NKAFKIPGAL NEDLPALNIL
     AEIIGSGPSA ILNKTFVDTR LGIYAYSSAT NFKEVGLFNI GVGFPTTSKH EDIDTKINEV
     IAKIKKEGVT QDEVNRVVAN ISAQTILARD GSGVIASELT EAIAAGDWTD YITGVDRLKK
     VTPADVLRVA QKYLVEDQST TGYFIPKQKG DQAQQSVQAN NFMPKNEPFY YRHLEGGHEH
     DEASSAIASE QKTRTNIASS LEETTIDKAP STYKREKISG IDVVSVKTSA KDFVTVAASI
     SLGNYANEGK NLAISSLTAS MLSKGTTLND KFKFSEKLQK LGVNISVNAS TTKVNIGFKC
     LKKDLDQVVT LLAEELRNPL FDAKEFENLK QQFTGSIQQN LNDPGQRGSI ALTQAIYPKA
     NPNYSTSVEE DLANVKNATL EEVKAFHKKY FGPASMHLVI VGDTEGANLN KSLQKSFKNW
     NGGIVENLKF EEAVKANAKT EVITIAEKPS AELYIGQYTG LKRADADYIP FYIGNYTLGA
     GFAGRLMQTV RDNDGLTYNI SSGMGGNINT GGYWMVNASF NPTLFQKGLD ATLVQVKKWV
     NDGITLEELE NKKTNLIGSF KVGMATTNGM TRTILGFVER GLEPSYIEQY PKDIEKVTLK
     QVNDAIKKYI QLDKLIIVKA GSLDKDGNPL K
//