ID A0A0D0EK20_9FLAO Unreviewed; 594 AA.
AC A0A0D0EK20;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=IW18_18010 {ECO:0000313|EMBL:KIO51535.1};
OS Flavobacterium hibernum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=37752 {ECO:0000313|EMBL:KIO51535.1, ECO:0000313|Proteomes:UP000032061};
RN [1] {ECO:0000313|EMBL:KIO51535.1, ECO:0000313|Proteomes:UP000032061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12611 {ECO:0000313|EMBL:KIO51535.1,
RC ECO:0000313|Proteomes:UP000032061};
RA Stropko S.J., Pipes S.E., Newman J.D.;
RT "Genome of Flavobacterium hibernum DSM 12611.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIO51535.1}.
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DR EMBL; JPRK01000015; KIO51535.1; -; Genomic_DNA.
DR RefSeq; WP_041519424.1; NZ_UGGR01000006.1.
DR AlphaFoldDB; A0A0D0EK20; -.
DR STRING; 37752.IW18_18010; -.
DR OrthoDB; 9124519at2; -.
DR Proteomes; UP000032061; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd19410; HK9-like_sensor; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR007891; CHASE3.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR Pfam; PF05227; CHASE3; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF08447; PAS_3; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:KIO51535.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000313|EMBL:KIO51535.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 244..297
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 369..594
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 594 AA; 68773 MW; 5272BEB51A4D316C CRC64;
MKWIPNFNSS NSLRVIFVVA VFILLFLSSI AYKHNRDLDE SSKVVMHTYE INIQLERLMS
AIKDAETGQR GYIITRNARF LTPYIYSRDK VNTSFIKLKK LTADNPKQQQ NLQKLFKLII
QRFVSFENCL KYSDPKTYDK RKLDNHMFGG RILMENIRFQ VDEMNDIEKN YLANRLKIYD
AEISLSPIFS ISLFLVALSF ILLAYRQISR DFERLKVYNK KLLISSGLIA ESEVIGKFST
WQWDLDTSKI DYSDNQYRLL GYEPNAFVPE KETFLNFVHP DDKETVAKSM EEIISKKQLP
FVYYKIVLPN HDIRYFKTTG KLLTDQQGSK ILLGINFDIT DEHLLNIELQ ERNSELEKSN
KELASFNHVA SHDLQEPLRK IQTFVSRISD ADKEVMSQSA RDYIAKIQIS AKRMRVLIDD
LLLFSRTNTT KKEFIKSNLN ELLENAKGEL TEVIDEKKAT ITTSKLPKLA VIPYQIEQLF
INLIGNSLKY SQPNIAPEIT IESHKVNSSD YPELLDQNVK KFHKITFTDN GMGFDPQFKE
TIFVLFQRLH SKTDYPGTGI GLAICKKIVD NHKGHIIADS TPNQGSVFTI FLPD
//
