ID A0A0D0F198_9FLAO Unreviewed; 547 AA.
AC A0A0D0F198;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Glycoside hydrolase {ECO:0000313|EMBL:KIO51772.1};
GN ORFNames=IW18_16040 {ECO:0000313|EMBL:KIO51772.1};
OS Flavobacterium hibernum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=37752 {ECO:0000313|EMBL:KIO51772.1, ECO:0000313|Proteomes:UP000032061};
RN [1] {ECO:0000313|EMBL:KIO51772.1, ECO:0000313|Proteomes:UP000032061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12611 {ECO:0000313|EMBL:KIO51772.1,
RC ECO:0000313|Proteomes:UP000032061};
RA Stropko S.J., Pipes S.E., Newman J.D.;
RT "Genome of Flavobacterium hibernum DSM 12611.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIO51772.1}.
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DR EMBL; JPRK01000013; KIO51772.1; -; Genomic_DNA.
DR RefSeq; WP_041518899.1; NZ_UGGR01000001.1.
DR AlphaFoldDB; A0A0D0F198; -.
DR STRING; 37752.IW18_16040; -.
DR OrthoDB; 9801455at2; -.
DR Proteomes; UP000032061; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd09001; GH43_FsAxh1-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF13; HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G00930)-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..547
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002226630"
FT DOMAIN 337..545
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 43
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 209
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 151
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 547 AA; 61577 MW; F65ECC5115BF0DD7 CRC64;
MKFKQLLLSL GLLCYLGVEA QGWNADLGNG KYKNPILHVD YSDPDVCAGK DGYYMTASSF
NSIPGLPILH SNDLVNWQLV GYGLQNQFPI EHYRTVCHGD GVWAPSIRYH NGEYYIYWGD
PDFGIYMVKT KDPKGVWEEP VLVKEAKGII DTCPFWDEDG KAYLSYAFAG SRANVKTVLM
LSELTPDGTK LIGNPALVFD GHDGHTTVEG SKMYKRDGYY WIMAPAGGVK PGWQLAMRSK
DVWGPYESKV VLHQGNTVMN GPHQGGYIET PNGDGWFIHF QDRWAYGRVV NLQPVTWKDN
WPIMGVDNDK DGIGEPVLEW TKPNVGKSYP ATPLVSSDEF NTHQFGLQWQ WQANQDPSKH
WGWSSANLGF MRLNCVPRDE TIKTMWMMPN LLLQKFPGDN FNATAKLTFA NNPEAGVSNS
GLIVFGEDYA YIAIEQDKTG NLNLTQRLMK NGRTSKEGEK EIALVPITQK EVYLRAKIEM
IQNKEPFDAR VTFYYSLDGK SFKKLGDSFK PTAGRWVGAK IGLFASGTKA VNDSSYADYD
WFRVESN
//
