ID A0A0D0FB12_9SPHI Unreviewed; 596 AA.
AC A0A0D0FB12;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:KIO79028.1};
GN ORFNames=TH53_00235 {ECO:0000313|EMBL:KIO79028.1};
OS Pedobacter lusitanus.
OC Bacteria; Bacteroidota; Sphingobacteriia; Sphingobacteriales;
OC Sphingobacteriaceae; Pedobacter.
OX NCBI_TaxID=1503925 {ECO:0000313|EMBL:KIO79028.1, ECO:0000313|Proteomes:UP000032049};
RN [1] {ECO:0000313|EMBL:KIO79028.1, ECO:0000313|Proteomes:UP000032049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NL19 {ECO:0000313|EMBL:KIO79028.1,
RC ECO:0000313|Proteomes:UP000032049};
RA Santos T., Caetano T., Covas C., Cruz A., Mendo S.;
RT "Draft genome sequence of Pedobacter sp. NL19 isolated from sludge of an
RT effluent treatment pond in an abandoned uranium mine.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIO79028.1}.
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DR EMBL; JXRA01000002; KIO79028.1; -; Genomic_DNA.
DR RefSeq; WP_041877223.1; NZ_JXRA01000002.1.
DR AlphaFoldDB; A0A0D0FB12; -.
DR STRING; 1503925.TH53_00235; -.
DR OrthoDB; 9812438at2; -.
DR Proteomes; UP000032049; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 2.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 64..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..344
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 356..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 383..406
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 469..528
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 534..594
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 596 AA; 65611 MW; D2F37E9073176944 CRC64;
MYVRLVNYLD AVNQYRRTKI SNRNFLVIAA MIVGVLAGLA AALLKTITHH IEDFLQDGFH
WQYKYYLFLV FPFIGILLSV MYVRRFIRKG KFETGLTPIL YTISKKSSRI EPHNIYSQII
TAALTVGFGG STGLEAPIVT SGGGIGSVVG RFLGLSYRET TMLLACGAAA GIAGAFNSPI
AGIVFAIEIL LPEFTIPAFI PLLLSSATAA VVARFFYNEQ LFFLVTEGWK FNSLIWYVVL
ALLIGLFSMY FTKANYFIKG LFYKIKHPYQ KVLAGGVVLG AMVFLFPTLY GEGYVTIKNL
LGGNYSAVIT NSIFSSYSNL PAVIILFTAI TVFAKSAATL VTLGAGGNGG IFAPSLIMGG
LIGFVLAFTI NTLGIAHVNV SNFIVAGMAA SLSAIMHAPL TGIFLIAEIT GGYVLMVPLM
ITSAISYLIN RSTNKYSIYT KPLAESGELM SHEDKDTTVL HMMKLKYLIE KDYLVLNEEE
TIAEKLPEIL QSRRNIFPVV AEDNIFKGLI YVEDVLKKAI NNPANADLTV HDLMQTAPAI
VFTTDSLKIV LKKMEKENAW LLPVLDEQEM YIGFVSKTAV FNKYRALLSR QADYME
//
