ID A0A0D0I0W2_9MICO Unreviewed; 326 AA.
AC A0A0D0I0W2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Dehydrogenase E1 component domain-containing protein {ECO:0000259|Pfam:PF00676};
GN ORFNames=SD72_04090 {ECO:0000313|EMBL:KIP53401.1};
OS Leucobacter komagatae.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Leucobacter.
OX NCBI_TaxID=55969 {ECO:0000313|EMBL:KIP53401.1, ECO:0000313|Proteomes:UP000032120};
RN [1] {ECO:0000313|EMBL:KIP53401.1, ECO:0000313|Proteomes:UP000032120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM ST2845 {ECO:0000313|EMBL:KIP53401.1,
RC ECO:0000313|Proteomes:UP000032120};
RA Karlyshev A.V., Kudryashova E.B.;
RT "Draft genome sequence of Leucobacter komagatae strain VKM ST2845.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIP53401.1}.
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DR EMBL; JXSQ01000003; KIP53401.1; -; Genomic_DNA.
DR RefSeq; WP_042543139.1; NZ_JXSQ01000003.1.
DR AlphaFoldDB; A0A0D0I0W2; -.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000032120; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF60; PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000032120}.
FT DOMAIN 17..312
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 326 AA; 34428 MW; AE4EBEEE21D3B871 CRC64;
MTDYQTAEHG LAGLELMAKI REFERRMPLL SEEGLIRGST HPSLGMEAVA VGVSLALRDD
DAIASTHRGH AHTLAKGADF GRTMAEILGR ADGYCGGKGG SMHIGVKEIG VLGTNGIVGA
GIGIATGAAL ASKMKGEDTV AVSYFGDGAS NQGVLAEAFN LAAIWNLPVI FVLENNHYAQ
SASIDDMVAQ PDLTKRGEAY GVPSFSGDGM NLQEVYELAS AAVARARAGE GPTLLVLDTY
RYLGHMAGDT EIYRSADEVE AAKANDPIDS LLAQLIEQGV ITQAEWDTKT KQLFEEVEAA
EQFARNSPFP DVSEAFTDVY AKGANA
//
