ID A0A0D0L949_9FLAO Unreviewed; 600 AA.
AC A0A0D0L949;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=RT99_20745 {ECO:0000313|EMBL:KIQ16496.1};
OS Flavobacterium sp. MEB061.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1587524 {ECO:0000313|EMBL:KIQ16496.1, ECO:0000313|Proteomes:UP000032091};
RN [1] {ECO:0000313|EMBL:KIQ16496.1, ECO:0000313|Proteomes:UP000032091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MEB061 {ECO:0000313|EMBL:KIQ16496.1,
RC ECO:0000313|Proteomes:UP000032091};
RA Perisin M.A., Vetter M., Gilbert J.A., Bergelson J.;
RT "16Stimator: statistical estimation of ribosomal gene copy numbers from
RT draft genome assemblies.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIQ16496.1}.
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DR EMBL; JXQR01000059; KIQ16496.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D0L949; -.
DR Proteomes; UP000032091; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KIQ16496.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..600
FT /note="Beta-glucuronidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002215847"
FT DOMAIN 41..201
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 206..295
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 297..536
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 600 AA; 69044 MW; F725A6D5A8141C74 CRC64;
MNKKARKIVF KKTRLLVLIM LFLGNYLQAQ TAMVNVESRH LSSLNGQWQV ILDPTRIGEW
KQVWLEKKPK SKTDFVEYSF DGGPMLKVPG DFNSQLCELT YFEGIVWYKK VFDYKSNNEK
RLFLNFGSVN YLADVYLNGE KIGSHEGGFT PFQFEITGKV KEGQNSLIVK ADNVRLQNGL
PGVGYDWFNY GGITRDVNLI ETSKTFIEDY AVQLKKGSLN KVLGWVQLNG SNVKQKIKIK
IPELNKTYKT ESDSKGRASL EFDSNLKLWS PENPKLYKVI IEAETDTIVD TIGFRCIEVQ
GNKVLLNKKS IFLKSVNIHE ENPNKGTRAY SKEDALLLLN SAKELGCNLV RLAHYPHNEN
MIKEAEKLGL MVWSELPIYQ HIQFSDSLVP KKMETMLKEM IHRDKNRCGV VIWSLSNETY
PGTPNRNNAL VELTQKCRAI DSTRLISHVA NTQSYTNNAF NVSDQLYEYS DLICINEYIG
WYNPWQGKPS DVKWNFSYPD KPVFISEFGA EALYGSNAGP TDEASGWTEE YQKQVYIDQI
EMFKTIPNLC GISPLLLFDY KSLGRMNQVY QKGYNRKGLL SEKGEKKKAW YIMNEYYKKR
//
