ID A0A0D0N9A4_KITGR Unreviewed; 487 AA.
AC A0A0D0N9A4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Betaine-aldehyde dehydrogenase {ECO:0000313|EMBL:KIQ64785.1};
GN ORFNames=TR51_11590 {ECO:0000313|EMBL:KIQ64785.1};
OS Kitasatospora griseola (Streptomyces griseolosporeus).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=2064 {ECO:0000313|EMBL:KIQ64785.1, ECO:0000313|Proteomes:UP000032066};
RN [1] {ECO:0000313|EMBL:KIQ64785.1, ECO:0000313|Proteomes:UP000032066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MF730-N6 {ECO:0000313|EMBL:KIQ64785.1,
RC ECO:0000313|Proteomes:UP000032066};
RA Arens J.C., Haltli B., Kerr R.G.;
RT "Draft genome sequence of Kitasatospora griseola MF730-N6, a bafilomycin,
RT terpentecin and satosporin producer.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIQ64785.1}.
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DR EMBL; JXZB01000002; KIQ64785.1; -; Genomic_DNA.
DR RefSeq; WP_043910605.1; NZ_JXZB01000002.1.
DR AlphaFoldDB; A0A0D0N9A4; -.
DR STRING; 2064.TR51_11590; -.
DR PATRIC; fig|2064.6.peg.2492; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000032066; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07093; ALDH_F8_HMSADH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR11699:SF211; ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1; 1.
DR PANTHER; PTHR11699; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000032066}.
FT DOMAIN 28..475
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 256
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 487 AA; 51922 MW; 196E5C9BF0DF9C38 CRC64;
MTGHLTTVAG VAVDTRHWIG GERVASAATF TDHSPIDGGV LGEIARGTAA EAHAAVAAAK
AAFPGWAATP RAERARLLHA VADGVERRLE DLAVVETADN GALLRSHRRG VMPRVAHNFR
FFADWLLTLD HEDFDTRGHT NHVSWDPAGP CVLITPWNAP LMLATWKIAP ALAAGNTVVL
KPAEWTPMTA SLLADIAAEA GLPAGVLNVV QGLGPEIGDA LTSHPDVRRI SFTGSVPTAR
HIAASAAANL TPLSLELGGK SPLLVFADAD LDLAVELAVE QYDNAGQVCL AATRLLVEES
VAEEFTRRFV ERAGQLKQGD PRELPTDLGP NIHERQLEKI DGFVQRAIGA GARAVIGGER
LAGRFYAPTL LTDVAQDSEI VQEEVFGPVL TLQTFRDEAE AVRLANDTRF GLAATLATGS
RERADRVTGQ LVAGTVWVNC FFVRDLQAPF GGSRHSGVGR EGGTWSFDFY CDVKNTVTAP
KGWQENG
//
