ID A0A0D0NF21_KITGR Unreviewed; 7590 AA.
AC A0A0D0NF21;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Polyketide synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=TR51_05530 {ECO:0000313|EMBL:KIQ66885.1};
OS Kitasatospora griseola (Streptomyces griseolosporeus).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=2064 {ECO:0000313|EMBL:KIQ66885.1, ECO:0000313|Proteomes:UP000032066};
RN [1] {ECO:0000313|EMBL:KIQ66885.1, ECO:0000313|Proteomes:UP000032066}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MF730-N6 {ECO:0000313|EMBL:KIQ66885.1,
RC ECO:0000313|Proteomes:UP000032066};
RA Arens J.C., Haltli B., Kerr R.G.;
RT "Draft genome sequence of Kitasatospora griseola MF730-N6, a bafilomycin,
RT terpentecin and satosporin producer.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIQ66885.1}.
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DR EMBL; JXZB01000001; KIQ66885.1; -; Genomic_DNA.
DR RefSeq; WP_043908455.1; NZ_JXZB01000001.1.
DR STRING; 2064.TR51_05530; -.
DR PATRIC; fig|2064.6.peg.1219; -.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000032066; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:1901362; P:organic cyclic compound biosynthetic process; IEA:UniProt.
DR CDD; cd05195; enoyl_red; 1.
DR CDD; cd08952; KR_1_SDR_x; 1.
DR CDD; cd08956; KR_3_FAS_SDR_x; 3.
DR CDD; cd00833; PKS; 5.
DR Gene3D; 3.30.70.3290; -; 5.
DR Gene3D; 3.40.47.10; -; 5.
DR Gene3D; 1.10.1200.10; ACP-like; 5.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 5.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 4.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 3.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR032821; PKS_assoc.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00698; Acyl_transf_1; 5.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR Pfam; PF16197; KAsynt_C_assoc; 5.
DR Pfam; PF00109; ketoacyl-synt; 5.
DR Pfam; PF02801; Ketoacyl-synt_C; 5.
DR Pfam; PF08659; KR; 4.
DR Pfam; PF21089; PKS_DH_N; 3.
DR Pfam; PF00550; PP-binding; 5.
DR Pfam; PF14765; PS-DH; 3.
DR SMART; SM00827; PKS_AT; 5.
DR SMART; SM00826; PKS_DH; 3.
DR SMART; SM00829; PKS_ER; 1.
DR SMART; SM00822; PKS_KR; 4.
DR SMART; SM00825; PKS_KS; 5.
DR SMART; SM00823; PKS_PP; 5.
DR SMART; SM01294; PKS_PP_betabranch; 4.
DR SUPFAM; SSF47336; ACP-like; 5.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 5.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 9.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 5.
DR SUPFAM; SSF53901; Thiolase-like; 5.
DR PROSITE; PS50075; CARRIER; 5.
DR PROSITE; PS00606; KS3_1; 4.
DR PROSITE; PS52004; KS3_2; 5.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 5.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Multifunctional enzyme {ECO:0000256|ARBA:ARBA00023268};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000032066};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 9..418
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 899..974
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 988..1411
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 2320..2395
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2407..2829
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 4202..4280
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4300..4724
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 5836..5911
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 5931..6352
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 7430..7505
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 854..895
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 7590 AA; 792333 MW; 0DA4A624101851EB CRC64;
MRFPLDSDAD RVAVIGIAGR LPKAPDPAAF WRLLCDGTDA ITAPPEGRQG ARRGGYLDRV
DGFDAAFFGI SPREAAGMDP QQRLMLELAW EALEDARIVP GTLTGGPTGV FVGSMWEDYT
SLTYPGHITP HTLTGTSRGV IANRVSHFLG VRGPSMTVDT AQSSALVAVH LAVESLRRGE
SVLALAGGVN LNLAAAREEG AEEFGGLSPD DRCFTFDARA NGFVRGEGGA FLVLKPLDRA
LADGDRVYGV IRGSAVNNDG ATQSLTVPSA QAQEQVIREA LARAGVRPAD VQYVELHGTG
TAVGDPVEAA ALAAAYRDPA ESGDADRALR VGSAKTNVGH LEGAAGIVGL LKTVLSVHHR
ALPPSLNYET PNPGIPLDAL ALRVQTALTP WPRPDAPLLA GVSSFGMGGT NAHVIVEQAP
DAAAPARRPA SEARPAPWIV TARTKQALRA QIARLHEHVR SHPDLTGAEV AHALATTRTR
FAHRAVLLDS VQVAADRAGA PGRTVFVFPG QGAQWVGMGR ELYAEYPVFR AAMDECARAL
APYTDWSLAE VLDGAPLDRV DVVQPALFAV MVSLAELWRS FGVEPDAVVG HSQGEIAAAY
VAGALSLSDA ARIVALRSRA LVALTGRGGM VSVALSAERA ADYVSRWDGA LTVAVVNAAG
SVVVSGDTQA LSELVAACEA DGVRARVVPV DYASHSAHVE AIRERLRTEL DGVRPQQGTV
PYYSAVTGGL LDDTTVLDAD YWYRNLREPV RFDLATAALL ADGHDVVVEV SPHPVLLPAL
EQSLEEARER TGASGVATGT LGRDRGGPDV FLTALSRLFV AGVPVDWSPA VAGAAPVDLP
TYAFQRRSYW LPGATAGQGG RTPADPATHA AGTAAPGRAD GGPETPDTGA GDTESADPVD
VAAVVIAQIA LVLGHEDPSE IDPALTFKEL GLDSVTGLEL RNRLAGALDR KLPSGLIFDR
PTPAELIDWL RTGPGDRSAP SAPAAHDDDP VVIVGMGCRF PGGVASPDDL WRLVADGVDA
IGDFPDDRGW DLGRLYDPEL RGAGTTYIDR GGFLEAVAGF DAPFFGISPR EALAMDPQQR
LVLETAWETF EHAGIDPASL RGSHTGVFTG VWSSGYATGP GLPEDLEGYL FTGVATSVTS
GRVAYHLGLR GPALSVDTAC SSSLVAVHLA AQALRAGECS LALAGGVTIM ATPFGFTEFS
RQHGLAADGR SKPFAAAADG TSWAEGAGLV LLERLSDARR NGHRVLAVVA GSAVNQDGAS
NGLTAPNGPS QERVIRQALA NAGLEPSEVD AVEAHGTGTT LGDPIEAHAL LAAYGQDRDE
PLWLGSVKSN IGHTQAAAGV AGLIKMVMAM RHGELPRTLH VDAPSPHVDW ASGGVRLLTE
ARPWPDHGHL RRAGVSAFGV SGTNAHLIIE QPAEPDPGHR PEPAGEAAPT AWLLSAKTDA
ALRAQAERLH AYATAHPDVP AAAISRALAA RTRFEHRAAV VGVDRDDLLS GLAALPPGLP
TRTGGTVFVF PGQGAQWTGM GRDLYEQSEV FRAGIDACAA ALDPYTDWSL VDELRHGSLD
RVDVVQPALF AVMVALADLW RSHGVQPDAV VGHSQAEIAA AYVAGALSLR DAAKVVALRS
RALAAIADRG GMVSLALSVE QAADYLARWG ERLTTAVVNG PAAVVVSGDL DVLDELGAAC
KADGIRFRRL PVNYAAHSAQ VEAIREQLLA DLADITPRSA AIPFYSTVTG EPVDTAGLDA
GYWYRNLREP VRFDLATARL TADGHDLFLE VGPHPVLVPA LDDVAATGTL RRDHGGLTEF
LAAAGRLHAA GVDVDWTPVL PRTAPAADLP TYAFQREPYW VTATPPAPRD DWRYQVAWAP
TSGTAAPVDP ARWLVLATTG HPWAEALRAR GFAVADSWDA DSRDAADTGD ARPDGVLSLL
ALDEAPHPDH PVLPAGLVRT LDLVRTLDPA RGPDPARPAA VPLWCATSGA VSTSGTDPVT
SPAQALAWGA GASAALEFPH GWGGLVDLPA VPDEDSVDAL LVVLAGTGED QVAIRGARRF
AKRLRRKAAS GPAAQPWRPR GTVLITGGTG ALGGHVARRL ARQGAEHIVL AARRGPDAPG
AAGLRDELEA AGARVTVAAC DVADRDALRD LVERVGDIRA VFHTAGAIKA TRLADTTVAE
FADVVTAKVA GAQNLAELLP DLDAFVLFSS TAGVWGDGHG AAYAAGNAFL DALAAQHRAG
GRATTSVAWG IWADGGMAAL ESVQRQRTLL GLGELDPGRA LDALQDVLDH DEALAVVTEA
DWAQFASAYT HARPSRLLRD LPEAQSRPQA PRPAPAAGGA DLLELITTHA AGVLGHATPE
RIDPRQAFKD LGFDSLTSVE LRNRLTAALG VKLPATLVFD HPTPARLAAH LSGEQDAPQA
PAAAATDEPI AVIGMGCRYP GGVGTPEDLW RLVADGADAV GEFPTDRGWD IDRLYDPTGS
RPRTSSTSKG GFLDAVGDFD AAFFGISPRE ALAMDPQQRI LLETAWETIE YAGIDPTTLE
GTSTGVFTGI WPTGYAAGPI PDDLEGYQVT GIASSVGSGR LAYQLGLLGP ALSLDTGCSS
SLVALHLAAQ ALRSGECSFA LAGGVTVNSA PTLFTEMSRQ GASAPDGRCK SFAAAADGAG
WAEGAGLLLL ERLSDARRNG HEVLAVVRGS ATNQDGASNG LTAPNGPSQE RVIRQALANA
GLEPSEVDAV EAHGTGTTLG DPIEAQALLA TYGRDRDEPL WLGSVKSNIG HAQAAAGVAG
LIKMVMAMRH GELPRTLHVD APTSHVDWES GAVRLLTEPV AWPGTGRPRR AGVSAFGISG
TNAHVILEQP AEADSAAPAP RGRADDQVLW PLSARSEAAL REQARRLAAF TAAHPEVGPA
AVGGALAART VFEHRAVVVG DVAALDALAE GGTVPGLVTG IARPLGRSVF VFPGQGAQWV
GMGGELYSSE PVFRDAIDAC DAALAPYTDW SLVEVLTGGG SLERVDVVQP ALFAVMVALA
ALWRAHGVEP DAVVGHSQGE IAAAYVAGAL SLEDAAKAVA LRSKALVALA GHGGMVSVVL
SADAAADYLS PWGDRITVAV VNSASTVVVS GEREALDELL AACAKDGIRA RAIPVDYAAH
SAQVEAIREQ LLTDLADLRP RPAAIPFYST VTAEPVDTAG LDAGYWYRNL REPVRFDLAT
ARLTADGHEV FVEVSPHPVL VQDLDGVATG TLRRDHGAIG EFHTALARLH VQGVAVTWPH
DRPHGVRLPR YAFQRSTYWL TPAAGDHGTG HPLAGTTVEL PDGTTVHSGR VSTRTHPWLA
DHAVDGTVLL PGTAFLELAT LAGGTLDDLV LHLPLALSDA PTDLQVSVGA PDDAGRSPVT
VHSRGGDGWV RHASGTLGGR VTAGRLDWPP RNAEPVDPEG FYAFLDGLGY QYGPAFRGVR
ELWQGEDELY AEVSVPDGAR FGVHPALLDA ALQPLILLSP DTRVRLPFSF SGVAVHATGV
SAARVHLART GADTYRATLT DLAGNPVADI TALTVRPAAE VRAAVLHTQW APLAASAPTE
VVPSPVLAAE ADAESVHALV QRARALVQDF LAEQPEPAAA RLAVLTRGVA GAAVRGLVRT
AAAEHPGRFV LVDMGDASEE DAVRAATTAG DEPELALRRE GVLVPRQARY APELTAPDGA
YRLSESGTGQ LDDLALLPWP EPALEPGQVR VAVRAAGLNF RDVLITLGMY PDRPPLGGEG
AGTVVEVGPG VTAWRPGDRV MGMISGAFGP RAVADHRLLT AIPDGWSFTE AASTPVAFTT
AWYGLFDLGE LRAGDRVLIH SGAGGVGMAA VQLALNSGAE VFATASPAKW DALRALGLDD
DHIASSRDTR FADRFPAMDV VLNSLAGELT DASLRLLADG GRFVELGKTD VRSPEGLIYR
AFDLNDVDPA RQGDILSSAV AMVADGTLEP LPVTAADLRQ AVASFRLMSQ ARHTGKIVLT
VPQPLDPDGT VLITGGTGTL GQAVARHLAS RHGVRHLLLL SRGGGAVPQL DAPEDVDVRV
VACDVADRDA LAAVLDSIPA AHPLTAVVHA AGVLDDTVVE RLTAEQLDRV LRPKVDGAWH
LHELTREHDL AAFVLFSAAA GVLGNAGQAG YAAANSYLDA FAAHRQALGL PAVSMAWGYW
EQESGMTAHL TAADRQRLAR KGIRPIGVDR ALAMFDTALA SGRPALTTAD LSMPQTLPTP
KAAASDLLSV VVAHTATVLG HSDAAAITPG LAFSDLGFDS LTAVELRNRL AGATGLRLPA
TLVFDHPTPA DLADHLTAQL SGAAGAVASV APVVGVAVSD DPVVIVGMGC RLPGGVGSPE
ELWGLVSGGV DAIGGFPSDR GWDVEGLFHP DADHPGTSYT RSGGFLADAA GFDADFFGIS
PREALAMDPQ QRVLLETAWE TFEDAGIDPT SLRGSQTGVF TGIWSSGYVG SPDQAPPDTE
GYLATGISPS ITSGRVSYLL GLQGQAVSVD SACSSSLMAI HLAAQALRSG ECTLALAGGV
TVSVTPLQFT EFSRQRALAA DGRCKPFSST ADGTAWGEGS GLVLLERLSD ARRNGHRVLA
VVRGSAVNQD GASNGLTAPS GPSQERVIRQ ALANAGLEPS EVDAVEAHGT GTTLGDPIEA
QALLATYGRD RAEPLWLGSV KSNLGHTQAA AGVAGVIKMV MAMRHGELPP TLHVQEPTPH
VQWDTGDIRL LTEARPWPET GRPRRAGISA FGASGTNAHV VIEQFAEETP EQPAADDSAE
PTVWLLSGKT DDALRAQARR LADHLTAHPE LRPTAIGRAL ATTRTRLAHR AALAGSTRTD
LMAELAALAD GDPRVITGVA GSPGRSVFVF PGQGAQWVGM GGELYGSEPV FRAAIDACDA
ALAPYTDWSL AEVLTGGGSL ERVDVVQPAL FAVMVALAEL WRAHGVEPDA VVGHSQGEIA
AAYVAGALSL EDAAKAVALR SKALVALADQ GGMVSVGLGH EQAAEFVARW DDRLTVAVVN
APDSVVVSGD LDALDELLTA CEADGIRARR LPVNYAAHSA QVEAIREQLL TDLAGIEPRT
AAVPFYSTVT GEEIDTAGLD ADYWYRNLRE PVRFDLAVET LTQHRHGVFV EVSPHPVLVP
VMDGVVTGTL RRDSGRQEFR LALARLHTQG VAVDWTPVFP GEPHHVPLPT YAFQHRPYWL
NPVAAKGDVS AAGLDSAGHP LLGAVVELAG DQSVLLTGRL STATRPWLAD HVVLGSVLLP
GTVFVELALH AGRQAGCDVL DELVLEAPMI LPDDGSVPVQ VVVGAPDGTG RRPVTVHSRT
GGSWLRHATG MLATADGPQP YDTGEPWQPA GEPVDLTDFY ETLADQGYEY GPVFAGVREI
RRQGDELYAE VALPVDTRDR FDLHPALLDA ALQPLTLLAA GRLPFSFAGV SMRKAGSTAR
VRLTPTGPDT FRVALADEAG PLAVIDALTV RHRPPGLLAA GTDQLFRLDW VPVESTGEAP
AVHHVTAPAG DPVAAAHTVA AETLGVLQDF LRDGDGRLAV VTRGAVGPDP VDLPSSVVWG
LVRAAQAEHP DRFVLVDTDD RVLVAGDEPQ LVVRDGTARA ARLVRAEAAP VPGPLDPNGT
VLITGGTGTL GRLVARHLRE RHGIRHLLLL SRTGAEVDFD AEVVACDVAD RDALAAVLDS
IPAAHPLTAV VHAAGVLDDG VVESLTPDRI DRVLRPKADA AWHLHELTKD LDLGAFVLFS
SAAGVLGGPG QANYAAANAF LDALAVHRRA LGLPGVSLAW GHWAEASGLT ENLTDTDLKR
LARAGVLPMP TDRALALFDL ALGADEPALV PAHLDLSATS TRPLLGRLTR TGPARRTNRP
GLGRELAALP ETEQHSRVLD LVTGQTAAVL GHTDTTAVGA DRAFKELGFD SLTAVELRNR
LSAVVGVRLP ATLTFDYPTP DALAGHLRNL LVGARRQAPA SPVPVGVPTS DDPVVVVGLG
ARYPGGVGSA QELWGLVSGG VDAVGDFPSD RGWDVGRLYD PAGGPGKSYT RSGGFLADAT
GFDAAFFGIS PREALAMDPQ QRVLLETVWE TFEDAGIDPT SLRGSRTGVF TGIWSSGYGA
GAQPPDLEGY LSTGTATSVT SGRVSYLLGL EGPAVSVDTA CSSSLVAIHL AAQALRSGEC
SLALAGGVTV MATPAGFVEF SRQRGLAADG RVKAFAEAAD GTAWGEGAGV VLLERLSDAR
RNGHRVLAVV RGSAVNQDGA SNGLTAPNGP SQERVIRQAL ANAGLEPSEV DAVEAHGTGT
TLGDPIEAQA LLATYGQGRV EPLWLGSVKS NLGHTQAAAG VAGVIKMVMA MRHGELPRTL
HVDAPTSHVD WASGNIRLLT EARPWPDNGH ARRAGISAFG ISGTNAHVIL EAPAAEPLPE
SPATPEPAAD VPVPWLLSAK SDEALRDQAR RLRGFLAEHP EVTPAEVAAD LAARARFPHR
AVLTDPVGLD ALIGGEPGIV TGTASPGRSA FVFSGQGGQW AGMGRGLYRE FPVFARALDE
VCGLLGLSVE VLFEDEEGVL GETLFTQGSV FALEVALFRL VESLGVRPDF VVGHSVGEVA
AAHVAGVLSL EDACALVGAR GRLMQELPGG GAMVSLQASV AEVVESLVPG AEVAAVNAAD
AVVVSGDEAA VAAVSEVWWG RGRRVRRLEV SHAFHSARMD PVLEELGRVA AGLSFGEPVI
PVVSTVAGCP VDMGEPGYWV RQVREPVRFA DAVEWLAGQG VTGFVEVGPH PVLVGNGLMR
RGGDSPERLF AGLGRLWADG AMRWSPPAIA TAGVRVPSYA FQHQHYWLQP TALAPIGDGR
LDHPLLRDAM ELPDDHGVVL TGQLATAAQP WLTEHVISGS PLLPGAAFVD LALRAGEHVD
CPAVEDLTLE TPLVVADGVQ VSVTVGPDRA GRRSVAIHSR ADGEWVRHAT GTLGAVPAAP
REPWARQWPP QAEAVDLDAF YDNLADAGFV YGTAFQGLRA AWRDGDTLYA EVAAPPGDSR
FALHPALLDA AIQIVTVADD RAKMPFSFAG ISSWRGAEHA RVRLTMTGED TCAIGLADQS
GAPVAEIASL TLRRPAGATT QDVPYRVAWP VLEAATTEPD IPVHHATSPV ETLRVIQDFL
RTDTPRMVVA TRNAVPVRPG EDVDPQAAAV WGLVRSAATE HPGRFVLVDG DGDGGKVRLA
GDEPQLAIRG GAVHVPRLER ARTEPLPSPL SPEGTVLVTG GTGTLGGTIA RHLAVRHGVR
HLLLVSRSGP DAPGAAALAA DLAALGATAD IVACDVADRE AVARLLAAHP VTSVVHAAGT
LADTVVESLT PQQFARVWEP KALAARHLHE LTSDLEAFVL FSSAAGVLGG AGQANYAAAN
AYLDGLAAHR HAEGQPAVSL AWGYWAEASG MTGGLSATDR HRLARAGVRP LPTADALALF
DAALTAGAPV LAPVRFDLPA LRRAGDPPAL LRELVRPRRR QAADREWTQA DVLQLVVGQV
ALVLGHASPE AVNPDQAFTD IGFDSLTAVE LRNQLDADTG LRLPATLVFD HPTPTRLAAF
VHTRLHGAAP DPLLAELDRL KSTLDAAAAD ADYETVASRL EGLLAAWTAN RTGAAAGVDE
ASDDELFSLL DDAHRRTEVI RSGESRNAEE
//
