ID A0A0D0X5F9_9ACTN Unreviewed; 543 AA.
AC A0A0D0X5F9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=ATP-dependent DNA helicase RecQ {ECO:0000313|EMBL:KIR66054.1};
GN ORFNames=TK50_12470 {ECO:0000313|EMBL:KIR66054.1};
OS Micromonospora haikouensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=686309 {ECO:0000313|EMBL:KIR66054.1, ECO:0000313|Proteomes:UP000032254};
RN [1] {ECO:0000313|EMBL:KIR66054.1, ECO:0000313|Proteomes:UP000032254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JXNU-1 {ECO:0000313|EMBL:KIR66054.1,
RC ECO:0000313|Proteomes:UP000032254};
RA Long Z., Huang Y., Jiang Y.;
RT "Sequencing and annotation of Micromonospora carbonacea strain JXNU-1
RT genome.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIR66054.1}.
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DR EMBL; JXSX01000001; KIR66054.1; -; Genomic_DNA.
DR RefSeq; WP_043962891.1; NZ_JXSX01000001.1.
DR AlphaFoldDB; A0A0D0X5F9; -.
DR PATRIC; fig|47853.6.peg.2637; -.
DR OrthoDB; 9760034at2; -.
DR Proteomes; UP000032254; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR021938; DUF3553.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF12073; DUF3553; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KIR66054.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000032254}.
FT DOMAIN 31..202
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 226..381
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 406..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 543 AA; 59643 MW; 13A5C2606994BEDE CRC64;
MKLSTHSMTL RRAARSLFGW KALRPNQLAA MRAVMKRRDA LVVLPTGAGK SAIYQIPASL
IPGPTVVISP LLALQQDQIA ALNERRRPEL RAVRISSDET PAQQAEAIEE VRAGRAEFLF
ITPEQLANPD RMAEVRSLKP ALVAIDEAHC ISAWGHDFRP DYLALGHLIE GIGRPPVVAL
TATASPPVRD DIVARLRLRD AEVVVSGLDR PNLFLEVAHC PTEDYRWRRL LALLREDRRP
GIIYVPTRRA AEELAARLTD AGFPAEFYHG GMPAGARGEL HEAFLADRVP IMVATSAFGM
GIDKPNIAWV VHMALPDSPD SYFQEIGRAG RDGEPARVLL LWQAEDVGLQ RFFSGGLPDA
TELRDLAALL RRKPATKKEL REATGLGPRK LGQYLALLEQ VGAAEPRSRQ RIGAPRYSPT
PVEAGDAARA EAERQQTVTR SRTDMMRAFA ETTGCRGQAL LAYFGEQMTK VCGHCDNCLA
GTSVADDGAS GPFPVHSQVR HPEWGPGMVL SYEEDRMTVL FEEVGYKTLS VRVVSEQGLL
TLD
//
