ID A0A0D0XAC2_9ACTN Unreviewed; 479 AA.
AC A0A0D0XAC2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II {ECO:0008006|Google:ProtNLM};
GN ORFNames=TK50_14690 {ECO:0000313|EMBL:KIR66365.1};
OS Micromonospora haikouensis.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=686309 {ECO:0000313|EMBL:KIR66365.1, ECO:0000313|Proteomes:UP000032254};
RN [1] {ECO:0000313|EMBL:KIR66365.1, ECO:0000313|Proteomes:UP000032254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JXNU-1 {ECO:0000313|EMBL:KIR66365.1,
RC ECO:0000313|Proteomes:UP000032254};
RA Long Z., Huang Y., Jiang Y.;
RT "Sequencing and annotation of Micromonospora carbonacea strain JXNU-1
RT genome.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIR66365.1}.
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DR EMBL; JXSX01000001; KIR66365.1; -; Genomic_DNA.
DR RefSeq; WP_043963256.1; NZ_JXSX01000001.1.
DR AlphaFoldDB; A0A0D0XAC2; -.
DR PATRIC; fig|47853.6.peg.3103; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000032254; Unassembled WGS sequence.
DR GO; GO:0016877; F:ligase activity, forming carbon-sulfur bonds; IEA:UniProt.
DR CDD; cd04433; AFD_class_I; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF1; NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000032254}.
FT DOMAIN 12..320
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 390..463
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
FT REGION 130..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 49147 MW; 1458B38ECF519FEA CRC64;
MSGPATLADA LAEVAGRSPH RPAVVAGDRT LTYAELLRRA DRLAAGLTGR AATVARCADD
VAVTVVAAAI ADVPLLVGDA RAADDERDRA RSLFRADRLV TGDGDRLTVE GLAGFAGLDG
FAAGDADRLA VAGHDGPPGD PGGDGPAGLG LSTSGSEGWP KCVERPWPAV TANARAFAAA
LELSPGEVVA CTTPPHHSYA LCGGLVTTLV AGGTYVALDQ RPGPRTVADA VDGHRVAVLL
SVPLLYRWFS TAGLATRHRP RLCVSAGAPL PPEDRRRWAE AVGWRIGEHY GTSEHGMLTL
DTESVAGSVG RPVAGVTLTV DPAPGPGDVL VSCAGPPTRV HAAGPAPGPA GHGPQPTGDV
GRLDGDGRLH LLGRRGGTLN VAGNKVPAAE VEDALRAFPA VRDCAVVGAP GPGGGQEVVA
FVETVRELDH RALYAFLHGR LAAYKVPARV VVVDRLPRNV NGKLLRSELL RGLAAGTWR
//
