ID A0A0D1EKK2_9RHOB Unreviewed; 713 AA.
AC A0A0D1EKK2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:KIT18129.1};
GN ORFNames=jaqu_01490 {ECO:0000313|EMBL:KIT18129.1};
OS Jannaschia aquimarina.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=935700 {ECO:0000313|EMBL:KIT18129.1, ECO:0000313|Proteomes:UP000032232};
RN [1] {ECO:0000313|EMBL:KIT18129.1, ECO:0000313|Proteomes:UP000032232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GSW-M26 {ECO:0000313|EMBL:KIT18129.1,
RC ECO:0000313|Proteomes:UP000032232};
RA Voget S., Daniel R.;
RT "Genome Sequence of Jannaschia aquimarina DSM28248, a member of the
RT Roseobacter clade.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the N-terminal section; belongs to the CRISPR-associated
CC nuclease Cas3-HD family. {ECO:0000256|ARBA:ARBA00006847}.
CC -!- SIMILARITY: In the central section; belongs to the CRISPR-associated
CC helicase Cas3 family. {ECO:0000256|ARBA:ARBA00009046}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIT18129.1}.
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DR EMBL; JYFE01000004; KIT18129.1; -; Genomic_DNA.
DR RefSeq; WP_043917012.1; NZ_JYFE01000004.1.
DR AlphaFoldDB; A0A0D1EKK2; -.
DR STRING; 935700.jaqu_01490; -.
DR PATRIC; fig|935700.4.peg.167; -.
DR OrthoDB; 9810236at2; -.
DR Proteomes; UP000032232; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR CDD; cd09641; Cas3''_I; 1.
DR CDD; cd17930; DEXHc_cas3; 1.
DR Gene3D; 1.10.3210.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006483; CRISPR-assoc_Cas3_HD.
DR InterPro; IPR038257; CRISPR-assoc_Cas3_HD_sf.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01596; cas3_HD; 1.
DR Pfam; PF18019; Cas3_HD; 1.
DR Pfam; PF00270; DEAD; 1.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51643; HD_CAS3; 1.
PE 3: Inferred from homology;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118};
KW ATP-binding {ECO:0000313|EMBL:KIT18129.1};
KW Helicase {ECO:0000313|EMBL:KIT18129.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000313|EMBL:KIT18129.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032232}.
FT DOMAIN 11..160
FT /note="HD Cas3-type"
FT /evidence="ECO:0000259|PROSITE:PS51643"
SQ SEQUENCE 713 AA; 76482 MW; 982AC3E9CFD9720B CRC64;
MIYAHSLADK PASEWETLEA HALQVAAAAR ARAEPFGAGE LAEVLGLLHD LGKIKAGFQR
KLSGEINDTA HSGEGAKVLW GGAARPLAAA IAGHHGRLPD PDRLRVRIAA AEAVTLPKWC
RLPDWEWPAR LREDKSLGSY RLQFLVRMLF GALCDADDRE TAAFYAGIPD RSPGVVTEAM
CAAFDVHMAG IGGEGSVNDL RRRVLSHGRD VASETPGLFT LTVPTGGGKT LTSLGFGLDH
ALAHGLRRLI YVIPYTSIIE QTVDVFRRVL GTDAVLEHHS NADWDGEDEA EAEQRRVSGA
SWDVPVVVTT AVQFFESLHA ARKKRCRKLP SLARSVIVLD EAQTMPLPLL RPCLAALREL
MEGYGASVVL STATQPALTK AGGFPAGEAL EGAREIAPEP AALFAALKRV EVRDVGSMDD
AALANRLRAE RRALCIVDNR MQARALFDAV RDADGAAHLS TLMVPAHRRA VLAEVRARLR
QGAPVRLVST SLIEAGVDVD FPVVLRAAAG IDSVAQAAGR CNREGRLDRG LVEVFRSEHP
APPAVEQFAA IGRAVLAEGH EDPIGEDAVA SYFRRLWGEY GEDALDAAEV HGVRGLLAAI
ARTPGACPYE QVEAAFRIIP GGERTVIVLD GPWGVGSNAL EAARFGSAGS VAKLVQSHAV
NVPWAMWSSM WEAGQIAWWA PDWFEEQFAV LQTSDLYDAE AGLSGVGEGA WVV
//
