ID A0A0D1L7G4_9MYCO Unreviewed; 1034 AA.
AC A0A0D1L7G4;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=FHA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=TL10_11330 {ECO:0000313|EMBL:KIU16885.1};
OS Mycolicibacterium llatzerense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=280871 {ECO:0000313|EMBL:KIU16885.1, ECO:0000313|Proteomes:UP000032221};
RN [1] {ECO:0000313|EMBL:KIU16885.1, ECO:0000313|Proteomes:UP000032221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLUC14 {ECO:0000313|EMBL:KIU16885.1,
RC ECO:0000313|Proteomes:UP000032221};
RA Greninger A.L., Langelier C., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium llatzerense and Mycobacterium immunogenum
RT recovered from brain abscess.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIU16885.1}.
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DR EMBL; JXST01000013; KIU16885.1; -; Genomic_DNA.
DR RefSeq; WP_043985722.1; NZ_JXST01000013.1.
DR AlphaFoldDB; A0A0D1L7G4; -.
DR STRING; 280871.TL10_11330; -.
DR PATRIC; fig|280871.6.peg.2349; -.
DR OrthoDB; 5242544at2; -.
DR Proteomes; UP000032221; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR041575; Rubredoxin_C.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR43429:SF3; NADH OXIDASE-RELATED; 1.
DR PANTHER; PTHR43429; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF18267; Rubredoxin_C; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000032221};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 19..73
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 516..610
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 1034 AA; 109961 MW; C6B7AB4AF36BDDFF CRC64;
MAEPPVIEVR EWGRPARRLT LSRPLLFGRE CDGVNLADGE VSRRHLRLVP SPMALSVVDL
GSSNGSTVNG VALTGRGTLS TGDVIRLGRT EIIVLHAPKP LTADQPPAAA VAHDPTRTMQ
MVKLLEVPVP AAAGTPVRPA GLRLAERALG IDPTGTKDLF PPYTELPHTI SRRVWQLARV
GSVLAYFAVV VTMFVRPAAG LFVFFRVIVP LWPALFFIAP GVWRNICPLS ASNQLPRVAG
FSRAATAPGW WTRNSFLMAA ALFFGIAGAR LAGLDRNGPA MGAVLAVIIA SAFAGGLAFK
GKSGWCSTIC PLLPLQRTYG QTPYVTSPNS HCESCVGCAK NCYDFKPRAA WQADMADPEP
RWSAPRVLFA AALPGFIIGF FTVHAQQGGT ATEKYGVLAL FVLVSVGLCY VLQAVTPLSQ
AMLTAGFAAV AINAYYWFSG PILTDSLRQI TGVDAPWLRW PITVVIGVLT LWWLARTRVS
ELQFAYLTGA RAEPVLLNTP TMPAAAAGPA AESGAVRVRF ESGSDPVGAD IGMSLLDVAE
SSGQAIEAGC RMGVCGADPV SIVEGMGCLS PAEADELKTL NRLGLGKSSR MACCARIQGG
DVTVSLTPER ADTTASRPVG YDRSIVSVVV IGNGIAGVTA ADFLRRGHPD CEIHVVGAEP
HGLYNRMGIS RLVYGRSAMQ GLYLLPEQWY DEHGVTAWLN TWATGIHLRS QLVRLGTGEK
LPYDRLVLAM GSSAAVPDIP GLNRPGSVVL RSAADAMRIR SYVQERRARH AVVAGGGLLG
LEAAYCLHQL GLRVTVLERG TRLLSKQIDA RCSQLVAEHF ARAGITITHK AETAEVRGDP
AVTGVRFKDG RILSCEVFLA ATGIRPNIEL ARDAGLPVGK GVLVDDRMQT RVPGVYAAGD
VAEHGGRVLG LWPVATEQAE AAAVNALGGD RTVPVETPPT ILKGVELELF SIGPVDPGPG
GEVVVIDRPA APSYRRLVVS RGRAVGATVL GHHPADLAAV QKAVREQRRV GPEALRVLRT
GNWEILSDAD RLAY
//
