ID A0A0D1LCD3_9MYCO Unreviewed; 506 AA.
AC A0A0D1LCD3;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=methylmalonate-semialdehyde dehydrogenase (CoA acylating) {ECO:0000256|ARBA:ARBA00013048};
DE EC=1.2.1.27 {ECO:0000256|ARBA:ARBA00013048};
GN ORFNames=TL10_03280 {ECO:0000313|EMBL:KIU18460.1};
OS Mycolicibacterium llatzerense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=280871 {ECO:0000313|EMBL:KIU18460.1, ECO:0000313|Proteomes:UP000032221};
RN [1] {ECO:0000313|EMBL:KIU18460.1, ECO:0000313|Proteomes:UP000032221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLUC14 {ECO:0000313|EMBL:KIU18460.1,
RC ECO:0000313|Proteomes:UP000032221};
RA Greninger A.L., Langelier C., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium llatzerense and Mycobacterium immunogenum
RT recovered from brain abscess.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIU18460.1}.
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DR EMBL; JXST01000003; KIU18460.1; -; Genomic_DNA.
DR RefSeq; WP_043401837.1; NZ_LIPZ01000030.1.
DR AlphaFoldDB; A0A0D1LCD3; -.
DR STRING; 280871.TL10_03280; -.
DR PATRIC; fig|280871.6.peg.665; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000032221; Unassembled WGS sequence.
DR GO; GO:0004491; F:methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity; IEA:InterPro.
DR CDD; cd07085; ALDH_F6_MMSDH; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010061; MeMal-semiAld_DH.
DR NCBIfam; TIGR01722; MMSDH; 1.
DR PANTHER; PTHR43866; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43866:SF4; MALONATE-SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000032221}.
FT DOMAIN 17..486
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 54459 MW; 0ED8D87C2F33AE00 CRC64;
MTTQIPHFIN GQRTTGESTR TADVLNPSTG QTQAQVLLAS VADVDTAVAG AVVAQREWAS
WNPQRRSRVL MKFIDLVNQN REELARLLSL EHGKTFEDSL GDIQRGVEVI EFAVGIPHLM
KGEFTEGAGS GIDVYSMRQP LGVVAGITPF NFPAMIPLWK AGPALACGNA IIIKPSERDP
SVPLRLAELF IEAGLPAGVL QVVNGDKEAV DAILQHPDVK AVGFVGSTDI AQYIYSTAAA
NGKRAQCFGG AKNHMIVMPD ADLDQAVDAL IGAGYGSAGE RCMAISVAVP VGEETANRLR
NKLVERVNQL RVGHSLDPKA DYGPLVTGAA LERVRNYIGQ GVDAGAELVV DGRERASDDL
TFDDADLSGG FFMGPTLFDH VTPDMSIYTD EIFGPVLVIV RAHDYEEALR LPSEHEYGNG
VAVFTRDGDT ARDFVSRVQV GMVGVNVPIP VPVSYHSFGG WKRSGFGDLN QYGTASIQFY
TKVKTVTERW PSGIKDGAEF SIPTFK
//
