ID A0A0D1LHY6_9MYCO Unreviewed; 497 AA.
AC A0A0D1LHY6;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Serine protease {ECO:0000313|EMBL:KIU18072.1};
GN ORFNames=TL10_05355 {ECO:0000313|EMBL:KIU18072.1};
OS Mycolicibacterium llatzerense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=280871 {ECO:0000313|EMBL:KIU18072.1, ECO:0000313|Proteomes:UP000032221};
RN [1] {ECO:0000313|EMBL:KIU18072.1, ECO:0000313|Proteomes:UP000032221}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLUC14 {ECO:0000313|EMBL:KIU18072.1,
RC ECO:0000313|Proteomes:UP000032221};
RA Greninger A.L., Langelier C., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium llatzerense and Mycobacterium immunogenum
RT recovered from brain abscess.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family.
CC {ECO:0000256|ARBA:ARBA00010541}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIU18072.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXST01000005; KIU18072.1; -; Genomic_DNA.
DR RefSeq; WP_043984797.1; NZ_JXST01000005.1.
DR AlphaFoldDB; A0A0D1LHY6; -.
DR STRING; 280871.TL10_05355; -.
DR PATRIC; fig|280871.6.peg.1101; -.
DR OrthoDB; 9758917at2; -.
DR Proteomes; UP000032221; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00987; PDZ_serine_protease; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR001940; Peptidase_S1C.
DR PANTHER; PTHR43343; PEPTIDASE S12; 1.
DR PANTHER; PTHR43343:SF3; PROTEASE DO-LIKE 8, CHLOROPLASTIC; 1.
DR Pfam; PF13180; PDZ_2; 1.
DR Pfam; PF13365; Trypsin_2; 1.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KIU18072.1};
KW Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:KIU18072.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032221};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 407..481
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 497 AA; 50899 MW; 6667E6A3079F76A2 CRC64;
MTNQDMSGDR PRLAPRPVTR TPVDPASQRA FGRPDGFTGS FLAEDQIRNQ GEYTPTNQAP
DPVLAEAFGR PGAATDSLQR HPADAGALAA EGKDDDEAVA DPWRDPSAAP SLGTPALPPP
PPVVVTAPVG KLGVRDVLFG RKVSMTALAV LAVLALVVGI VGGVVGRKTA EVVEAFTTSK
VTLKTSDGGD LPAGRFAKVA AAVADSVVTI EAMGDTDGSQ GSGVVVDGRG YVVTNNHVIS
DAAKDPSKYH ISVVFNDGKQ VPANLVGRDP KTDLAVLKVD NVDNLTVAKF GDAEKVKVGD
EVIAAGAPLG LRSTVTHGII SALHRPVPLS GEGSDTDTVI DGIQTDASIN HGNSGGPLIN
MNSEVIGINT AGKSLSDSAS GLGFAIPVNE VKATVEVLIK DGKIFHPTLG LNAKSASDKV
ASGAQVVNVV AGSPAEKGGI LENDVVVKVG PRKVADADEF VVAVRQLQIG QPAPIEVIRD
GRHVTLTVVP NADTPAS
//
