ID A0A0D1W7G9_9EURO Unreviewed; 525 AA.
AC A0A0D1W7G9;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 24.
DE RecName: Full=Acetyl-CoA hydrolase {ECO:0000256|ARBA:ARBA00017958};
DE EC=3.1.2.1 {ECO:0000256|ARBA:ARBA00011920};
DE AltName: Full=Acetyl-CoA deacylase {ECO:0000256|ARBA:ARBA00029672};
GN ORFNames=PV11_00413 {ECO:0000313|EMBL:KIV84640.1};
OS Exophiala sideris.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV84640.1, ECO:0000313|Proteomes:UP000053599};
RN [1] {ECO:0000313|EMBL:KIV84640.1, ECO:0000313|Proteomes:UP000053599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV84640.1,
RC ECO:0000313|Proteomes:UP000053599};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala sideris CBS121828.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O = acetate + CoA + H(+); Xref=Rhea:RHEA:20289,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=3.1.2.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001831};
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KN846951; KIV84640.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D1W7G9; -.
DR STRING; 1016849.A0A0D1W7G9; -.
DR HOGENOM; CLU_019748_3_0_1; -.
DR OrthoDB; 100792at2759; -.
DR Proteomes; UP000053599; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0003986; F:acetyl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR43609; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR43609:SF1; ACETYL-COA HYDROLASE; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:KIV84640.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053599}.
FT DOMAIN 12..230
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 333..483
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 525 AA; 58043 MW; 5465505A74A4EB19 CRC64;
MAASALLKSR CRRASYLNKL CKAEDLIDLF PNGTYVGWSG FTGVGYPKKV PTALADHVEK
NNLQGKLKYN LFVGASSGAE TENRWAKLNM IERRAPHQVG KEIAKGINNG NIKFFDKHLS
MFPVDLMYGY YTKHKANNRL DVAIVEASAI TEDGGIIPGA SVGASPEIIQ MADKIIIEVN
TAAPSFEGLH DITMTDLPPR RKPYLIMSPE DRIGTPHIPV DPERVVAVVE SDYPDQTTEN
APEDDTSRAI ASNLIEFLQH EVKHGRLPAN LLPIQSGIGN IANAVVGGLA KGGANFKNLK
VWTEVLQDSF LDLFDSGNLD FATATSIRFS PGGFKRFYDG WEQYHAKLLL RSQQVSNSPE
IIRRLGVIGM NTPVEVDIYA HANSTCVMGS RMLNGLGGSA DFLRSAKYSI MHTPSTRPSK
TDPTGVSCIV PMCTHVDQTE HDLDVIVTEI GLADVRGMSP RERAREIIKQ CAHPDYRPIL
EDYFNKAEFE CLRKGMGHEP HLLFQAFDMH RNFAENGTMK ISGWK
//
