ID A0A0D1W863_ANEMI Unreviewed; 370 AA.
AC A0A0D1W863;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=AF333_15165 {ECO:0000313|EMBL:KON96612.1}, SAMN04487909_11959
GN {ECO:0000313|EMBL:SDJ50607.1};
OS Aneurinibacillus migulanus (Bacillus migulanus).
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
OC Aneurinibacillus group; Aneurinibacillus.
OX NCBI_TaxID=47500 {ECO:0000313|EMBL:KON96612.1, ECO:0000313|Proteomes:UP000037269};
RN [1] {ECO:0000313|EMBL:KON96612.1, ECO:0000313|Proteomes:UP000037269}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2895 {ECO:0000313|EMBL:KON96612.1,
RC ECO:0000313|Proteomes:UP000037269};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Chen Z., Lan J., Che J., Ge C.,
RA Shi H., Pan Z., Liu X.;
RT "Fjat-14205 dsm 2895.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SDJ50607.1, ECO:0000313|Proteomes:UP000182836}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2895 {ECO:0000313|EMBL:SDJ50607.1,
RC ECO:0000313|Proteomes:UP000182836};
RA de Groot N.N.;
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
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DR EMBL; LGUG01000004; KON96612.1; -; Genomic_DNA.
DR EMBL; FNED01000019; SDJ50607.1; -; Genomic_DNA.
DR RefSeq; WP_043066589.1; NZ_LGUG01000004.1.
DR AlphaFoldDB; A0A0D1W863; -.
DR STRING; 47500.AF333_15165; -.
DR PATRIC; fig|47500.8.peg.664; -.
DR OrthoDB; 9775794at2; -.
DR Proteomes; UP000037269; Unassembled WGS sequence.
DR Proteomes; UP000182836; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000037269}.
FT DOMAIN 19..356
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 370 AA; 41708 MW; FBAE41BCD35E150F CRC64;
MENTVQTNNE VLFYVEKGIG HILLNRPKAL NALSLYMVDE IGKKLAEWEH NPSVSLVLIE
GAGEKGLCAG GDMRSFYDKR DDNVEEYALQ FFSIEYKMNL ALHRYTKPVL AYMNGIVMGG
GIGVSIFASH RVVTERSKLS MPEMNIGFFP DVGGSYFLNQ MPGQMGRYLA LTAHLFNGAD
AIYLGAADYY IQSEQWTELK NDVQIEDWTQ VGNREQISAR LTEILTKYGT ANLPESPLAK
VQDKVDRHFN HHSVADILAS LDRSAAEGDE WAAETAKTLR EKSPISMAVA LEQLVRGKGM
TAADCFWMEM NMSMHFMHSH DFYEGVRSVL VDKDRNPSWN PATIQEVKQE HVEVFFKNPW
EGGQHPLADE
//
