ID A0A0D1WQR2_9EURO Unreviewed; 1643 AA.
AC A0A0D1WQR2;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV11_09218 {ECO:0000313|EMBL:KIV77421.1};
OS Exophiala sideris.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV77421.1, ECO:0000313|Proteomes:UP000053599};
RN [1] {ECO:0000313|EMBL:KIV77421.1, ECO:0000313|Proteomes:UP000053599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV77421.1,
RC ECO:0000313|Proteomes:UP000053599};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala sideris CBS121828.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KN846954; KIV77421.1; -; Genomic_DNA.
DR STRING; 1016849.A0A0D1WQR2; -.
DR HOGENOM; CLU_001485_20_2_1; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000053599; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF3; KINESIN FAMILY MEMBER 14-LIKE; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}; Reference proteome {ECO:0000313|Proteomes:UP000053599};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 16..367
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1506..1634
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 612..652
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..712
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 732..754
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1459..1486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 796..831
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 634..652
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 118..125
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1643 AA; 183151 MW; 0DDB10DEE603A7CF CRC64;
MAPTGGGTAG GGGGGNIKVV VRVRPFNNRE IDRNAKCIVQ MQGAQTVLQP PPEADERLRK
GGKAGSEAQR TFKFDQSYWS FNKGDSHYAG QDNLFNDLGT PLLDNAFQGY NNCIFAYGQT
GSGKSYSMMG YGEEVGVIPR ICRDMFERIN AVQSDVNLTC TVEVSYLEIY NERVRDLLNP
ATKGNLRVRE HPSTGPYVED LAKLAVRSFN EIENLMDEGN KARTVAATNM NETSSRSHAV
FTLTLTQKRH DVETSMDTEK VAKISLVDLA GSERATSTGA TGARLKEGAE INRSLSTLGR
VIAALADLSS GKKGMKVPYR DSVLTWLLKD SLGGNSMTAM IAAISPADIN FEETLSTLRY
ADSAKRIKNH AVVNEDPNAR MIRELKEELA KLRSQLGGAG APGMAEETYP PDTPLDKQMV
SITQVDGSIK RVSKAEIMDQ LSQSEKLYGD LNQTWEEKLQ KTEEIHKERE AALEELGISI
EKGNVGMSTP KKMPHLVNLS DDPLLAECLV YNLKPGVTTV GNVDSSEASE IRLNGSRILD
HHCKLENVDN VVTVIPEEGA AVMVNGVRVD KATRLKSGNR IILGDFHIFR FNNPLEAKAE
RAERSLLRHS VTASQLNSPT PFRPAHERSW SAAGSEFDGS SSRAQSPGMN NKDSDWLLAR
REAAGALLGS DPKIMQLTDE ELDNLFANVQ RAREERRGRP ENRIYEHDED SDDLSSFLVR
DKYMSNGTAD NFSVDTALTQ PGTPSQHGDS QEDGDVTLTQ DQFEEQGEQQ VKPEIEVNRT
PSVAHAGQDD EQEVQAIQMQ KELELAKKQF QEELQKQKDA FEAQIKKMDL DVRTREATRS
PSGFLPLDAN ELAIARNVVE KWQQRNYVLI AEAVLQNASL LKEAQVMAKL LDPDCNFQYV
ILDLGQDRSS SYDLILHDIS GDEDDALANA RKPCLAVRVV DNQLKCIHLW SVEKLRSRVN
KMRQMHQYKN EPEYLQHFRM DNPFRDSDQP LFSLVGDGSI PLTAVFETRV QDFVVEICSP
STQQIIGRVR MSLEPSLTES PPHTIKFNII LRDLVGFSEH EGTQVHAQMT VLGTSDESVA
TTQPIHGFGD GPIRFESIHN LSVRRASEKS ATMKIAIFAQ VSSTHLDKLL SWDELREMNE
QGPDQDIAHR LPESEYNVEE RHDVFVKVQM LELAENGQYM PIEVLQTSAD DNGAFQLHQG
LQRRISITLT HSLTESLPWD DLKGLRVGEV HLIDSSGRIA DIGSVTPDIP LKQIQEPMIK
DNADGTSNIS LLGQWDSSLH KSLLLDRATN EQCRIQIALR WDVVSSRLEQ SMTFSIEQQL
QILPRSFVRP QSMFKSLWTQ TRITHATDGL FSIVVRPISA QRAADLWRLD TSRNYIKGEE
LLGSWKARGI SMVKDYLVTR RKKRQLQDIE SAKAAFGLKK LSLSKSRTRA ASPSNIDARE
EALLRKFLTI WEKPSIEMSN PVFNNDDGSD SPQADTRSTN TPDLNAVSGR KTRYLATVTS
VPKNVTSLKS GYLLMPSENH EPGHSQSMQW KRRFVDLRPP YLYIHSVPDG EGINAINLTH
ARIDHDPDFK RLLGSGSSIS SGDGVSGHKR SGSAELHGLA HVFAVYGEQN TFLFAARSES
QKMEWILKID QSYFEGEDEG EEA
//
