ID A0A0D1WUV1_EXOME Unreviewed; 354 AA.
AC A0A0D1WUV1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Enoyl reductase (ER) domain-containing protein {ECO:0000259|SMART:SM00829};
GN ORFNames=PV10_04285 {ECO:0000313|EMBL:KIV93040.1};
OS Exophiala mesophila (Black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=212818 {ECO:0000313|EMBL:KIV93040.1, ECO:0000313|Proteomes:UP000054302};
RN [1] {ECO:0000313|EMBL:KIV93040.1, ECO:0000313|Proteomes:UP000054302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 40295 {ECO:0000313|EMBL:KIV93040.1,
RC ECO:0000313|Proteomes:UP000054302};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala mesophila CBS40295.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KN847522; KIV93040.1; -; Genomic_DNA.
DR RefSeq; XP_016224614.1; XM_016368826.1.
DR AlphaFoldDB; A0A0D1WUV1; -.
DR GeneID; 27322130; -.
DR VEuPathDB; FungiDB:PV10_04285; -.
DR HOGENOM; CLU_026673_29_2_1; -.
DR OMA; TGITAYW; -.
DR OrthoDB; 179761at2759; -.
DR Proteomes; UP000054302; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205:SF42; ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530); 1.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054302}.
FT DOMAIN 21..341
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 354 AA; 38395 MW; EBC98024E02A90F8 CRC64;
MSSTYKTVVL AKRPKADIIP GETFKLKTDN PKPTANDLKD GQVLFQSNYL SIDPAMRGWL
NDTRSYVPPV QIGEVMRGHV IGTIIASKDP KFPVGSHATA MAGWSEFAVI TTSDKTQSLE
KIQVPKGGQL TDGLAVLGIT GLTAYFGILD VGKVKAGDFV VVSGAAGATG SVVGQIAKLK
GATVLGLAGS DDKVRWLTEE LGFDSALNYK DPDFFKKFRA ATKNLIDVFF DNVGGDILDL
ALSRAKPHAR FVMCGGISQY NSAVQKGPKN YLMIVSMRIR MEGFIVFDYA KEYPRALRDL
SQWLSEGKIK RKETIVKGGL DQAQKALQDL YKGINTGKLL VEVKPVDQKL SASL
//
