ID A0A0D1X1T5_EXOME Unreviewed; 612 AA.
AC A0A0D1X1T5;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=PV10_03355 {ECO:0000313|EMBL:KIV95735.1};
OS Exophiala mesophila (Black yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=212818 {ECO:0000313|EMBL:KIV95735.1, ECO:0000313|Proteomes:UP000054302};
RN [1] {ECO:0000313|EMBL:KIV95735.1, ECO:0000313|Proteomes:UP000054302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 40295 {ECO:0000313|EMBL:KIV95735.1,
RC ECO:0000313|Proteomes:UP000054302};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala mesophila CBS40295.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; KN847521; KIV95735.1; -; Genomic_DNA.
DR RefSeq; XP_016227309.1; XM_016367791.1.
DR AlphaFoldDB; A0A0D1X1T5; -.
DR STRING; 212818.A0A0D1X1T5; -.
DR GeneID; 27321200; -.
DR VEuPathDB; FungiDB:PV10_03355; -.
DR HOGENOM; CLU_014831_6_0_1; -.
DR OMA; PVKSHHG; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000054302; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:InterPro.
DR GO; GO:0097027; F:ubiquitin-protein transferase activator activity; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF68; FI02843P; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054302};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 325..391
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 335..376
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 418..453
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 549..582
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 84..178
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 156..178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 612 AA; 65753 MW; 43723CA87917EE80 CRC64;
MATTSVSTPL KSHHGIFSTK TAGGRMPLTP SRRARTASAA TKISSTSPCT PPRKDQSIHK
SDPSTFFSRS ISRSVSKFAY ANSPKSNIAR SRNSPKGLEL GVSDWTLTGT GPAVSGTPLR
ERSKKEGPLR SRPGKTTIRL PHNTADRFIP SRTASAGLAT AGSGKSDENT RPRTAGQDGS
TVLANAASAF DISARGADSD ITTALEGLGL DDNTTSTYGR ADPDSVAYES SLASACGIST
TQRILEFKPA PPESSKPIDL RSQYNRPLKQ ASAQSAQFRR RVQSAPERVL DAPDIADDYY
LNLLDWGSGN QVAIGLKRNV YVWSAESGTV SCLLETSPDT YVSSVKWSGD GAYVGVGLGT
GEVQIWDVEE GTKLRSMFGH DTRVGVMGWN KHTLSTGARS GLVFNHDVRV QDHKIAELVS
HTSEVCGLEW RSDGAQLATG GNDNLVSIWD ARSLAAPKFA KKNHRAAVKA LSWCPWQLNL
LATGGGYNDR HIHFWNTTTG ARVNSVDTGS QVTSLKWSNH YRELVSSGGF PDNSLTIWSY
PTLVRNVEIP AHESRVLHSC LSPDGQMLAT AAADESLKFW KVFERKAGIS AAASREGGVG
KNGQMAKQMT IR
//
