ID   A0A0D1Y7H6_9EURO        Unreviewed;       756 AA.
AC   A0A0D1Y7H6;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=VWFA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=PV11_08680 {ECO:0000313|EMBL:KIV76819.1};
OS   Exophiala sideris.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV76819.1, ECO:0000313|Proteomes:UP000053599};
RN   [1] {ECO:0000313|EMBL:KIV76819.1, ECO:0000313|Proteomes:UP000053599}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV76819.1,
RC   ECO:0000313|Proteomes:UP000053599};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala sideris CBS121828.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN846954; KIV76819.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D1Y7H6; -.
DR   STRING; 1016849.A0A0D1Y7H6; -.
DR   OrthoDB; 1933598at2759; -.
DR   Proteomes; UP000053599; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006974; P:DNA damage response; IEA:UniProt.
DR   CDD; cd00198; vWFA; 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR041298; UBZ3.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF18439; zf_UBZ; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
DR   PROSITE; PS51907; ZF_UBZ3; 1.
PE   4: Predicted;
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053599};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          21..55
FT                   /note="UBZ3-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51907"
FT   DOMAIN          523..756
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          55..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        58..74
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   756 AA;  86477 MW;  1D096DB60A9BFDFE CRC64;
     MDSKTNIYDI DQKNSLNDSQ QVADQYVCDQ CHQSISTYQR GEHNDWHFAK SLDEQETGEA
     AEATQPQFVS NVKQPDIRQD KDQRNDQPPT YAPPSHPPPK IVSGVTGPIL AHTNQVIEAA
     KIRARDEQQM QNALQNLQLQ YHIYNTEIEP EHEADYYCNC PIHNYQRMKW NRYGVQEMWS
     KAVMYPGEKS YNDNKQNIGL LSRNPYRLRV VSPYGFYQSA WGVSRPQPGY HAQSIHQTIA
     LNNSLNRQAQ ADIDDKEPKV NIWDDDALSA AMSQVRIAAA NDKKQALDLS NGNGTDGRGE
     KPSSTSAGTK SEKSKISRFS SFRQSIGIRS SEEKVVAKTE KVVYKGREVR DAILAEENAR
     WPDEQWRYIV QVYQEKVGMT RKIADLRNRH PIQYLHMLRA GYFEPIPVAW ANQASNPLKF
     SIEAAGGWRG ITPTWRGYED TAEERLYWVL NHREGSVGMR MKPDFISEMD MARARMAKAV
     EPPPEYFSST DTCHLQHTSE GYSKQVMPAP FLAYDRPEVP TDDTMILLDV SGSMDFDPLR
     PNYNQYLITG YSKSTQPKNK DVAKAIIRRF TDAMSNHDHA FQGYDLTTFS SQANYIGTIN
     HKNLNDMWRK VRIGGGTRVM TGWQKVKELH FQKHSESATH HPVYGWQAGP ETPMLRLLLL
     LDGEATDMDE FELDLLGLSW AHVTIFLIGV DGCPHHHRHA NELQRISDVN HHVSFVDAQG
     NTPERFVTHE LLKRHLGYEL SMSEFEQIEE LPGYSE
//