ID A0A0D1Y8P7_9EURO Unreviewed; 648 AA.
AC A0A0D1Y8P7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Lysyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030563};
GN ORFNames=PV08_10666 {ECO:0000313|EMBL:KIW11366.1};
OS Exophiala spinifera.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW11366.1, ECO:0000313|Proteomes:UP000053328};
RN [1] {ECO:0000313|EMBL:KIW11366.1, ECO:0000313|Proteomes:UP000053328}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW11366.1,
RC ECO:0000313|Proteomes:UP000053328};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala spinifera CBS89968.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
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DR EMBL; KN847499; KIW11366.1; -; Genomic_DNA.
DR RefSeq; XP_016231582.1; XM_016384980.1.
DR AlphaFoldDB; A0A0D1Y8P7; -.
DR STRING; 91928.A0A0D1Y8P7; -.
DR GeneID; 27337749; -.
DR VEuPathDB; FungiDB:PV08_10666; -.
DR HOGENOM; CLU_008255_6_0_1; -.
DR OrthoDB; 648039at2759; -.
DR Proteomes; UP000053328; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004824; F:lysine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006430; P:lysyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR004364; Aa-tRNA-synt_II.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR018149; Lys-tRNA-synth_II_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004365; NA-bd_OB_tRNA.
DR PANTHER; PTHR42918:SF5; LYSINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42918; LYSYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00152; tRNA-synt_2; 1.
DR Pfam; PF01336; tRNA_anti-codon; 1.
DR PRINTS; PR00982; TRNASYNTHLYS.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:KIW11366.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053328}.
FT DOMAIN 294..647
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 648 AA; 72362 MW; 3B7CA3FC5F317AE7 CRC64;
MNSTRRQILP KLKRRHGEIS PGELHPTPPP HHFFITLGHA ATLMSSRSAW QIWQTSRLLA
PARSPGFRAG SIHKLRHHRK PASTLQWLPA AQFSTTVPKP SNYEVPDRDL VYSNKEVEER
MRELAPVGTN LHPRYAPAGQ ERDIKTLVSE FEDNEGAAIP ENDSAADIKV AGRISSIRSS
GSKLVFLDLV KDQSKIQVTI SHASLASDIA LDAFKRQTRL IRRGDYVSIR GSLPFRSKNG
QITIKASELP VLLSPCLNRF PVEQPGFATS ETSESNFTPR HVEMLTDPEV ISTFKARSAL
IRAMRSFFEQ LSFVEVSTPI LSASAGGATA KPFETSSTHF DRKLALRIAP ELYLKRLMIG
GMTRIFEIGP SFRNEGVDKT HNPEFYTCEF YAVDHELSQL KAYTHQLLTV IANAIQTLPM
APSSEQSCLL IKQIGEGEHF AEFDFISTLN SELGSDLPNL SSPDAQKNLI EIFETKSLPI
PSNPTVPRLV DKLASIYIEP KSLDEPIWIT NIPECLSPLA KSYVHPSAPN SQRVAARAEL
FIQGKEVVNC YEEENSPFEQ RRKFTDQQRL ARQNEDQDIV DEEAMLVDED YIQALEWGLP
PTGGWGCGID RLVMLFTGRE RIGDVLSFGT LRAVTRGAEQ KDSLDVPS
//
