ID A0A0D1Y8V7_9EURO Unreviewed; 639 AA.
AC A0A0D1Y8V7;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE RecName: Full=Nucleolar protein 58 {ECO:0000256|ARBA:ARBA00020379};
GN ORFNames=PV11_06913 {ECO:0000313|EMBL:KIV79347.1};
OS Exophiala sideris.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1016849 {ECO:0000313|EMBL:KIV79347.1, ECO:0000313|Proteomes:UP000053599};
RN [1] {ECO:0000313|EMBL:KIV79347.1, ECO:0000313|Proteomes:UP000053599}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121828 {ECO:0000313|EMBL:KIV79347.1,
RC ECO:0000313|Proteomes:UP000053599};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala sideris CBS121828.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules.
CC {ECO:0000256|ARBA:ARBA00024837}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; KN846953; KIV79347.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D1Y8V7; -.
DR STRING; 1016849.A0A0D1Y8V7; -.
DR HOGENOM; CLU_015495_5_0_1; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000053599; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053599};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 285..413
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 415..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 477..501
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..554
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 639 AA; 69526 MW; 4F75F8415A9B392C CRC64;
MTLLILTETS AGYALLKAKD KKLLKRDDLA SELDSVENVT SLLKLKEFQK FDSAAAALEE
AAAIVEGKVT PKLSSLLDTL KDEKKISLAV ADPKLGNAIG KLPGLDIKAV ADSTTADLYR
AIREHLPSLI PGLMPEDVKT MSLGLSHSLA RHKLKFSPDK IDVMIVQAIG LLDDLDKELN
TYAMRVKEWY GWHFPEMAKI LNDNLAYAKV VLKMGMRTNF ENCDLADILP EEIEAAVKAA
ADRSMGTEIT DEDLENIQML AEQVVAFTEY RTQLSSYLTA RMTAIAPNLT TLVGELVGAR
LIAHAGSLLN LSKSPASTIQ ILGAEKALFR ALKTKHDTPK YGLIYHASLI GQASGKNKGK
MARVLAAKAA LGLRVDALQD WGDDEANIPE DEKAALGLEA RANLERKLAA MEGKPLKPRG
VAIGPNGTPA TSQPKKWEIK EARKYNPDAD GLAGDEAPAK EKSKKGKKLI EEIPEDKTMA
DGDDDEEESE SQPDEPIDSD EVDAIVPSKV NGINGASEKT AKKAEKDRKH AEKTASKEAK
KGKKGDKDAA NEETKLEILA AQCGLSVERY KRKLERGEIQ FSEDGVPTAI SKKDIKKAKK
AADKSAANGE SEGSKKRKRT EDEIEPSKSE GKKKRKEKS
//
