ID A0A0D1YKF1_9PEZI Unreviewed; 832 AA.
AC A0A0D1YKF1;
DT 29-APR-2015, integrated into UniProtKB/TrEMBL.
DT 29-APR-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=CSC1/OSCA1-like 7TM region domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PV09_07119 {ECO:0000313|EMBL:KIW01347.1};
OS Verruconis gallopava.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Venturiales; Sympoventuriaceae; Verruconis.
OX NCBI_TaxID=253628 {ECO:0000313|EMBL:KIW01347.1, ECO:0000313|Proteomes:UP000053259};
RN [1] {ECO:0000313|EMBL:KIW01347.1, ECO:0000313|Proteomes:UP000053259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 43764 {ECO:0000313|EMBL:KIW01347.1,
RC ECO:0000313|Proteomes:UP000053259};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Ochroconis gallopava CBS43764.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KN847555; KIW01347.1; -; Genomic_DNA.
DR RefSeq; XP_016211216.1; XM_016360844.1.
DR AlphaFoldDB; A0A0D1YKF1; -.
DR STRING; 253628.A0A0D1YKF1; -.
DR GeneID; 27315092; -.
DR VEuPathDB; FungiDB:PV09_07119; -.
DR HOGENOM; CLU_002458_0_0_1; -.
DR InParanoid; A0A0D1YKF1; -.
DR OrthoDB; 366603at2759; -.
DR Proteomes; UP000053259; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053259};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 438..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..509
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..550
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 626..646
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..672
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 693..710
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 716..734
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 27..196
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 218..423
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 434..706
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 295..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 812..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 832 AA; 94967 MW; DCFCE940EE6D5888 CRC64;
MTFHTSVLGD SDDSYGKRIV GEPKDTVLQI GISVVLGSIA FLAFCILRPR WPGMYAARKK
SRSAADSLPE LPNTLFGWIP MIWRITDAQV LHSAGLDAYV FLAFFKMAIK FLCITLPVAL
LIIKPVHDRF PEPTGDKHHK NKTETALGNL LHQDLKRNVH NGSDSFVPIP EFDADYLWMY
LVFAYLFTFL ALYLIIVESK RIIEVRQEWL GAQTTVTDRT IRLSGIPPEL RSEDKIKEVI
EDLDIGTVES VVMCRDWKEL DKTMETRMKV LRRLEEAWTV YLGRRRVERS LETLPIAQPA
PPGPAVDPED REDSTLLPAN GANGNSSEVP YARTRPTTRI WYGRFRLRYK VVDAIDYYEE
QLRRIDKRIR QLRKKEFKAC PLAFVTMNSV ATAQMTVQAV LDSHPMQLLA NTSPSPADVI
WSNTYLSRGQ RMFRSWSITA FISILTIFWS VVFVPIAGLI DLNRIHSVFP GLAEALDAHP
LAKSLVQTQL STLGASLLLV LVPYFYWWLS TLQGMISQGD IELSVISKNF FFVFFNFFIV
FTALGTAALA PDDFANQTPR EIANKLALKI QELRNFYVNY IILQGLGLFP MRLLEFGSVF
LYPIGLIGAK TPRDYAEAMQ PPMFSYGFYL PQNILIFLIC IVYSVLRSSW QVLLPGLLYF
IIGYFVHKYQ LLYAMDHRQH STGGSWAMIC DRIIVGLIIF QVTMAGQLAL RFAIKRSLLI
IPLVAMTLWF SYVYSNRYKP LMKFIALRSI RRHEQANQLS SRLLMEQRVR PIDLDEVTDE
PAERDMRFIN PSLVAPLENV WILDKAARAE SIMSRSPPPE EDDPRSLNSA VA
//
