ID   A0A0D1YPW4_9EURO        Unreviewed;      1432 AA.
AC   A0A0D1YPW4;
DT   29-APR-2015, integrated into UniProtKB/TrEMBL.
DT   29-APR-2015, sequence version 1.
DT   08-NOV-2023, entry version 28.
DE   RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN   ORFNames=PV08_04462 {ECO:0000313|EMBL:KIW17271.1};
OS   Exophiala spinifera.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX   NCBI_TaxID=91928 {ECO:0000313|EMBL:KIW17271.1, ECO:0000313|Proteomes:UP000053328};
RN   [1] {ECO:0000313|EMBL:KIW17271.1, ECO:0000313|Proteomes:UP000053328}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 89968 {ECO:0000313|EMBL:KIW17271.1,
RC   ECO:0000313|Proteomes:UP000053328};
RG   The Broad Institute Genomics Platform;
RA   Cuomo C., de Hoog S., Gorbushina A., Stielow B., Teixiera M.,
RA   Abouelleil A., Chapman S.B., Priest M., Young S.K., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Exophiala spinifera CBS89968.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KN847494; KIW17271.1; -; Genomic_DNA.
DR   RefSeq; XP_016237487.1; XM_016378810.1.
DR   STRING; 91928.A0A0D1YPW4; -.
DR   GeneID; 27331545; -.
DR   VEuPathDB; FungiDB:PV08_04462; -.
DR   HOGENOM; CLU_003828_0_0_1; -.
DR   OrthoDB; 20915at2759; -.
DR   Proteomes; UP000053328; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR018515; Tuberin-type_domain.
DR   InterPro; IPR027107; Tuberin/Ral-act_asu.
DR   InterPro; IPR024584; Tuberin_N.
DR   PANTHER; PTHR10063; TUBERIN; 1.
DR   PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR   Pfam; PF11864; DUF3384; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF03542; Tuberin; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053328}.
FT   DOMAIN          1144..1378
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1389..1416
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1432 AA;  160041 MW;  D82A4DA3853E35C8 CRC64;
     MLITGRPERR SHRMSTGNDT ARERSATGGG DKESRRRSVW NVPVLTPKFL PDDVISQDRH
     TEKAAPAEMP VIPEDVLDDG YKLVDSPDEA RVWLLSFGDF KPGTEVSMKF LNLRVGARSL
     LSLLSKLLLA WTTKADKARR DNKASRSASL KEIKNLDWLL QYICDYLSIG HSDFDSLELA
     QTVETVTTFC LNASRYADIN SGINILYAIA SHFEFPKSGL EQTLVVLCAS IANLQETPDH
     LFDCNKLLAT SDLSGEVLTI LYSFIRVPTL DNNSKNLAHA RGSTHLLRNL IDERLKDGQY
     VVNLQQFIGE LHTAASEGIF RFSHDILASV HAILSASRLT EIQALDFGKI LEIILLCLEM
     TPSRPVNPTQ NLLTPVISPD EDKTRVYERH YRERETMTKK LAEDFQSLWK HLSPANQDTV
     NEFFLDFPHF ADNEQIKCAL ALAETKYLSS GDNERKNQYI RDLHERTVQN QQLAAASRIC
     AIQVLVRACN VHASSPTSDE QVDDLYGWML SEILSQVAIE QDGQVLAELF LALQEMVSNY
     EEAAKHTQSI MSMIKTLKEL VLLSSARGIF TDTHAAEATK ILATVFCYGV HLDAAVAVEV
     FDALQNIAGS TCHFRPARLV AKRLLFRVRA DDAGFIYVIS DSESQHIASA LLRTRESADA
     FEAPNTQRHS ASSASISTKS DLHEPMWMYP ETEDVTYLFA DRPSTYLNVD ASSNPESQTE
     LDMDTWLMNI IRCLQADTDW ETYSYTIIHV AAQLSNIALF LNSMEAVVKF RQVLCEQIVN
     NTFREAPPPI GLKKSDVALC MFNILVPLIA YATMKHEAVQ KGFGDDLVRA FLAGIAGAWE
     GTSRPCIHAL SICSLEIPSS VASLYPTIID KMSKNMTQVH LTAHILEFLI HMAMLPEMHS
     NLNADEIQMI FGICIQFLEK TREQHQASVA SPAGRLSLQS RHSGLNFRRP PYRASMLTDI
     GLPQYAAALA YHVIIFWFLA LRLESRAKYV SWIVARLIWK NSQGLEMIDE QSQVLIDMMQ
     RTAFSDLGET APQADFAGQN DGPIFSASWI AGLSVITAQT AGHTGKTQII KRQASGTTYA
     RYQPLTTELP SHHTPSHTEI RHHEVTTEIL PSHIILQMVA SAATTNVADQ PVLLPDEDYV
     RRALDSFDRI PTVSSHKIGV LYIGKDQSAE SDYLANTSGS QDYERFLSEL GYRVSLQPPL
     HYNPQGLEFP RDGENTIAWR NRVDEIVYHV PTMMPTDLEE DPQCITKKAH VGNCHVNVVF
     NRSGLPWSME NFKSQLNYIN IVIRPACRGR QALDPNFMPG FYWVQVITRD DLPNISPVAD
     TKIISAAQLA PFVRALALNA SMFSQCWNTR DSDSEFPSGW RARLQQIKRL KERVISKVAE
     KQGVAGTSSG TVNTVVAGTQ GGRRTPVPRD EAGGSRKDVT LASQLDFSSW TV
//